Systemic nicardipine as an adjunct to combat vasospasm after prior flap failure

Brett F. Michelotti, Samer Rajjoub, T. Shane Johnson

Research output: Contribution to journalArticle

Abstract

Unrecognized or untreated vasospasm in microsurgery can lead to flap hypoperfusion and failure. Numerous strategies have been explored for their efficacy in potentiating vasodilation. We present a case of unrecognized vasospasm leading to flap failure followed by a second free flap reconstruction in which severe vasospasm was treated with systemic nicardipine used as an adjunct to other more commonly employed antispasmodics. Although the literature investigating the use of systemic calcium channel blockade in microsurgery is limited, it should be considered an alternative when addressing arterial vasospasm.

Original languageEnglish (US)
Article numbere54
JournalPlastic and Reconstructive Surgery - Global Open
Volume1
Issue number7
DOIs
StatePublished - Jan 1 2013

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Nicardipine
Microsurgery
Parasympatholytics
Free Tissue Flaps
Calcium Channels
Vasodilation

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

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title = "Systemic nicardipine as an adjunct to combat vasospasm after prior flap failure",
abstract = "Unrecognized or untreated vasospasm in microsurgery can lead to flap hypoperfusion and failure. Numerous strategies have been explored for their efficacy in potentiating vasodilation. We present a case of unrecognized vasospasm leading to flap failure followed by a second free flap reconstruction in which severe vasospasm was treated with systemic nicardipine used as an adjunct to other more commonly employed antispasmodics. Although the literature investigating the use of systemic calcium channel blockade in microsurgery is limited, it should be considered an alternative when addressing arterial vasospasm.",
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Systemic nicardipine as an adjunct to combat vasospasm after prior flap failure. / Michelotti, Brett F.; Rajjoub, Samer; Johnson, T. Shane.

In: Plastic and Reconstructive Surgery - Global Open, Vol. 1, No. 7, e54, 01.01.2013.

Research output: Contribution to journalArticle

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