Tamoxifen‐induced remission in breast cancer by escalating the dose to 40 mg daily after progression on 20 mg daily: A case report and review of the literature

Andrea Manni, Baha'uddin M. Arafah

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

An 80‐year‐old woman with metastatic breast cancer to the lungs and bones was treated with tamoxifen, 10 mg twice daily, with arrest of disease of six month's duration. At the time of progression, increasing the dosage to 20 mg twice daily resulted in an objective remission now lasting 8+ months. This finding indicates that in this patient, the taxoxifen dosage of 40 mg/daily had a significantly higher anti‐tumor effect than 20 mg/daily. Pertinent literature on the correlation of response with tamoxifen dosage is reviewed.

Original languageEnglish (US)
Pages (from-to)873-875
Number of pages3
JournalCancer
Volume48
Issue number4
DOIs
StatePublished - Aug 15 1981

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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