Teflon granuloma results in a false-positive "second primary" on 18F-2-deoxyglucose positron emission tomography in a patient with a history of nasopharyngeal cancer

Jonathon L. Chadwick, Ayesha Khalid, Henry Wagner, Brendan C. Stack

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

18F-2-deoxyglucose positron emission tomography (PET) is a frequent diagnostic tool used to evaluate patients with head and neck squamous cell carcinoma (HNSCC). 18F-2-deoxyglucose-PET is used in this setting for detection of metastases (staging) and/or second primaries. False-positive PET scans (10%-15% frequency) can distract from accurate HNSCC staging and an orderly prescription for treatment. Teflon (DuPont, Wilmington, DE) vocal fold injections can result in granuloma formation that has been described to generate a false-positive uptake on PET. We present a case of an injected vocal cord that appeared as a second laryngeal primary in a patient with recurrent nasopharyngeal cancer.

Original languageEnglish (US)
Pages (from-to)251-253
Number of pages3
JournalAmerican Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume28
Issue number4
DOIs
StatePublished - Jul 1 2007

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Nasopharyngeal Neoplasms
Deoxyglucose
Polytetrafluoroethylene
Granuloma
Positron-Emission Tomography
Vocal Cords
Prescriptions
Neoplasm Metastasis
Injections
Carcinoma, squamous cell of head and neck

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

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title = "Teflon granuloma results in a false-positive {"}second primary{"} on 18F-2-deoxyglucose positron emission tomography in a patient with a history of nasopharyngeal cancer",
abstract = "18F-2-deoxyglucose positron emission tomography (PET) is a frequent diagnostic tool used to evaluate patients with head and neck squamous cell carcinoma (HNSCC). 18F-2-deoxyglucose-PET is used in this setting for detection of metastases (staging) and/or second primaries. False-positive PET scans (10{\%}-15{\%} frequency) can distract from accurate HNSCC staging and an orderly prescription for treatment. Teflon (DuPont, Wilmington, DE) vocal fold injections can result in granuloma formation that has been described to generate a false-positive uptake on PET. We present a case of an injected vocal cord that appeared as a second laryngeal primary in a patient with recurrent nasopharyngeal cancer.",
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T1 - Teflon granuloma results in a false-positive "second primary" on 18F-2-deoxyglucose positron emission tomography in a patient with a history of nasopharyngeal cancer

AU - Chadwick, Jonathon L.

AU - Khalid, Ayesha

AU - Wagner, Henry

AU - Stack, Brendan C.

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AB - 18F-2-deoxyglucose positron emission tomography (PET) is a frequent diagnostic tool used to evaluate patients with head and neck squamous cell carcinoma (HNSCC). 18F-2-deoxyglucose-PET is used in this setting for detection of metastases (staging) and/or second primaries. False-positive PET scans (10%-15% frequency) can distract from accurate HNSCC staging and an orderly prescription for treatment. Teflon (DuPont, Wilmington, DE) vocal fold injections can result in granuloma formation that has been described to generate a false-positive uptake on PET. We present a case of an injected vocal cord that appeared as a second laryngeal primary in a patient with recurrent nasopharyngeal cancer.

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