Teflon laryngeal granuloma presenting as laryngeal cancer on combined positron emission tomography and computed tomography scanning

Research output: Contribution to journalArticle

Abstract

Background: Positron emission tomography with 18F-fluorodeoxyglucose ( 18FDG) has been increasingly used in the diagnostic investigation of patients with neoplasms of the head and neck. Positron emission tomography and computed tomography have also proven useful for surveillance of thyroid cancers that no longer concentrate radioiodine. However, certain benign or inflammatory lesions can also accumulate 18F-fluorodeoxyglucose and lead to misdiagnosis. Objectives: We review and discuss the pitfalls of using positron emission tomography and computed tomography for surveillance of thyroid cancer. Method: We present the case of a 48-year-old woman who was diagnosed with a laryngeal neoplasm on integrated positron emission tomography and computed tomography scanning, after a routine ultrasound demonstrated an enlarged thyroid nodule. On physical examination, she had a laryngeal mass overlying an immobile vocal fold. The mass was biopsied and found to harbour a Teflon granuloma. Conclusions: Positron emission tomography positive Teflon granulomas have previously been reported in the nasopharynx and vocal folds, and should be considered in the differential diagnosis of patients who have undergone prior surgery involving Teflon injection. It is important for otolaryngologists and radiologists to recognise potential causes of false positive positron emission tomography and computed tomography findings, including Teflon granulomas.

Original languageEnglish (US)
Pages (from-to)575-578
Number of pages4
JournalJournal of Laryngology and Otology
Volume123
Issue number5
DOIs
StatePublished - May 1 2009

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Laryngeal Granuloma
Laryngeal Neoplasms
Polytetrafluoroethylene
Granuloma
Vocal Cords
Fluorodeoxyglucose F18
Thyroid Neoplasms
Positron-Emission Tomography
Thyroid Nodule
Nasopharynx
Head and Neck Neoplasms
Diagnostic Errors
Physical Examination
Differential Diagnosis
Injections
Positron Emission Tomography Computed Tomography

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Cite this

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title = "Teflon laryngeal granuloma presenting as laryngeal cancer on combined positron emission tomography and computed tomography scanning",
abstract = "Background: Positron emission tomography with 18F-fluorodeoxyglucose ( 18FDG) has been increasingly used in the diagnostic investigation of patients with neoplasms of the head and neck. Positron emission tomography and computed tomography have also proven useful for surveillance of thyroid cancers that no longer concentrate radioiodine. However, certain benign or inflammatory lesions can also accumulate 18F-fluorodeoxyglucose and lead to misdiagnosis. Objectives: We review and discuss the pitfalls of using positron emission tomography and computed tomography for surveillance of thyroid cancer. Method: We present the case of a 48-year-old woman who was diagnosed with a laryngeal neoplasm on integrated positron emission tomography and computed tomography scanning, after a routine ultrasound demonstrated an enlarged thyroid nodule. On physical examination, she had a laryngeal mass overlying an immobile vocal fold. The mass was biopsied and found to harbour a Teflon granuloma. Conclusions: Positron emission tomography positive Teflon granulomas have previously been reported in the nasopharynx and vocal folds, and should be considered in the differential diagnosis of patients who have undergone prior surgery involving Teflon injection. It is important for otolaryngologists and radiologists to recognise potential causes of false positive positron emission tomography and computed tomography findings, including Teflon granulomas.",
author = "Ondik, {M. P.} and J. Kang and Michael Bayerl and Michael Bruno and David Goldenberg",
year = "2009",
month = "5",
day = "1",
doi = "10.1017/S0022215108003988",
language = "English (US)",
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pages = "575--578",
journal = "Journal of Laryngology and Otology",
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TY - JOUR

T1 - Teflon laryngeal granuloma presenting as laryngeal cancer on combined positron emission tomography and computed tomography scanning

AU - Ondik, M. P.

AU - Kang, J.

AU - Bayerl, Michael

AU - Bruno, Michael

AU - Goldenberg, David

PY - 2009/5/1

Y1 - 2009/5/1

N2 - Background: Positron emission tomography with 18F-fluorodeoxyglucose ( 18FDG) has been increasingly used in the diagnostic investigation of patients with neoplasms of the head and neck. Positron emission tomography and computed tomography have also proven useful for surveillance of thyroid cancers that no longer concentrate radioiodine. However, certain benign or inflammatory lesions can also accumulate 18F-fluorodeoxyglucose and lead to misdiagnosis. Objectives: We review and discuss the pitfalls of using positron emission tomography and computed tomography for surveillance of thyroid cancer. Method: We present the case of a 48-year-old woman who was diagnosed with a laryngeal neoplasm on integrated positron emission tomography and computed tomography scanning, after a routine ultrasound demonstrated an enlarged thyroid nodule. On physical examination, she had a laryngeal mass overlying an immobile vocal fold. The mass was biopsied and found to harbour a Teflon granuloma. Conclusions: Positron emission tomography positive Teflon granulomas have previously been reported in the nasopharynx and vocal folds, and should be considered in the differential diagnosis of patients who have undergone prior surgery involving Teflon injection. It is important for otolaryngologists and radiologists to recognise potential causes of false positive positron emission tomography and computed tomography findings, including Teflon granulomas.

AB - Background: Positron emission tomography with 18F-fluorodeoxyglucose ( 18FDG) has been increasingly used in the diagnostic investigation of patients with neoplasms of the head and neck. Positron emission tomography and computed tomography have also proven useful for surveillance of thyroid cancers that no longer concentrate radioiodine. However, certain benign or inflammatory lesions can also accumulate 18F-fluorodeoxyglucose and lead to misdiagnosis. Objectives: We review and discuss the pitfalls of using positron emission tomography and computed tomography for surveillance of thyroid cancer. Method: We present the case of a 48-year-old woman who was diagnosed with a laryngeal neoplasm on integrated positron emission tomography and computed tomography scanning, after a routine ultrasound demonstrated an enlarged thyroid nodule. On physical examination, she had a laryngeal mass overlying an immobile vocal fold. The mass was biopsied and found to harbour a Teflon granuloma. Conclusions: Positron emission tomography positive Teflon granulomas have previously been reported in the nasopharynx and vocal folds, and should be considered in the differential diagnosis of patients who have undergone prior surgery involving Teflon injection. It is important for otolaryngologists and radiologists to recognise potential causes of false positive positron emission tomography and computed tomography findings, including Teflon granulomas.

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