Telomeric (TTAGGG)(n) sequences are associated with nucleolus organizer regions (NORs) in the wood lemming

Wan Sheng Liu, Karl Fredga

Research output: Contribution to journalArticle

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Abstract

The distribution of the (TTAGGG)(n) telomeric sequence was studied in chromosomes of the wood lemming, Myopus schisticolor, by fluorescence in-situ hybridization. As expected, the hybridization signals were observed at telomeres of all chromosomes. However, quite a number of interstitial telomeric sites were present in the pericentric heterochromatic regions. Consistent strong hybridization signals were also seen at one terminus of chromosomes 5, 7 and 12-15. By post-hybridization G-banding and silver-staining, the large blocks of the telomeric sequences on chromosomes 5 and 12 were localized to nucleolus organizer regions (NORs).

Original languageEnglish (US)
Pages (from-to)235-240
Number of pages6
JournalChromosome Research
Volume7
Issue number3
DOIs
StatePublished - Jun 15 1999

All Science Journal Classification (ASJC) codes

  • Genetics

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