Temperature-Dependent Pre-Bloodmeal Period and Temperature-Driven Asynchrony between Parasite Development and Mosquito Biting Rate Reduce Malaria Transmission Intensity

Krijn P. Paaijmans, Lauren J. Cator, Matthew Brian Thomas

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

A mosquito needs to bite at least twice for malaria transmission to occur: once to acquire parasites and, after these parasites complete their development in their mosquito host, once to transmit the parasites to the next vertebrate host. Here we investigate the relationship between temperature, parasite development, and biting frequency in a mosquito-rodent malaria model system. We show that the pre-bloodmeal period (the time lag between mosquito emergence and first bloodmeal) increases at lower temperatures. In addition, parasite development time and feeding exhibit different thermal sensitivities such that mosquitoes might not be ready to feed at the point at which the parasite is ready to be transmitted. Exploring these effects using a simple theoretical model of human malaria shows that delays in infection and transmission can reduce the vectorial capacity of malaria mosquitoes by 20 to over 60%, depending on temperature. These delays have important implications for disease epidemiology and control, and should be considered in future transmission models.

Original languageEnglish (US)
Article numbere55777
JournalPLoS One
Volume8
Issue number1
DOIs
StatePublished - Jan 31 2013

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biting rates
Culicidae
malaria
Malaria
Parasites
parasites
Temperature
temperature
vectorial capacity
Epidemiology
Infectious Disease Transmission
Bites and Stings
Vertebrates
eclosion
epidemiology
Rodentia
rodents
Theoretical Models
Hot Temperature
vertebrates

All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

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Temperature-Dependent Pre-Bloodmeal Period and Temperature-Driven Asynchrony between Parasite Development and Mosquito Biting Rate Reduce Malaria Transmission Intensity. / Paaijmans, Krijn P.; Cator, Lauren J.; Thomas, Matthew Brian.

In: PLoS One, Vol. 8, No. 1, e55777, 31.01.2013.

Research output: Contribution to journalArticle

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