Temperature elevations in prostatic tumors during laser photothermal therapy

L. Zhu, Anilchandra Attaluri, H. Cai, R. Edziah, E. Lalanne, C. Bieberich, R. Ma, A. M. Johnson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In vivo experiments were performed to measure temperature elevations in prostatic tumors implanted in mice during laser photothermal therapy using nanorods. Ti:Sapphire laser tuned at 800 nm irradiating the surface of the tumor delivered an average laser power of 0.5 - 1.0 W, equivalent to a laser radiance of 1.3-2.6 W/cm2. The temperature elevations measured by two thermocouples located at the center and bottom of the tumor have shown non-uniform tumor temperature field, 10-30°C above the baseline temperature of 37°C. The experimental studies have demonstrated the capability of confining laser energy in tumors by a very small amount of nanorod solution.

Original languageEnglish (US)
Title of host publicationSmart Biomedical and Physiological Sensor Technology VIII
Volume8025
DOIs
StatePublished - Sep 26 2011
EventSmart Biomedical and Physiological Sensor Technology VIII - Orlando, FL, United States
Duration: Apr 28 2011Apr 28 2011

Other

OtherSmart Biomedical and Physiological Sensor Technology VIII
CountryUnited States
CityOrlando, FL
Period4/28/114/28/11

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Zhu, L., Attaluri, A., Cai, H., Edziah, R., Lalanne, E., Bieberich, C., Ma, R., & Johnson, A. M. (2011). Temperature elevations in prostatic tumors during laser photothermal therapy. In Smart Biomedical and Physiological Sensor Technology VIII (Vol. 8025). [80250G] https://doi.org/10.1117/12.882746