Abstract
Patients with schizophrenia are known to have impairments in sensory processing. In order to understand the specific temporal perception deficits of schizophrenia, we investigated and determined to what extent impairments in temporal integration can be dissociated from attention deployment using Attentional Blink (AB). Our findings showed that there was no evident deficit in the deployment of attention in patients with schizophrenia. However, patients showed an increased temporal integration deficit within a hundred-millisecond timescale. The degree of such integration dysfunction was correlated with the clinical manifestations of schizophrenia. There was no difference between individuals with/without schizotypal personality disorder in temporal integration. Differently from previous studies using the AB, we did not find a significant impairment in deployment of attention in schizophrenia. Instead, we used both theoretical and empirical approaches to show that previous findings (using the suppression ratio to correct for the baseline difference) produced a systematic exaggeration of the attention deficits. Instead, we modulated the perceptual difficulty of the task to bring the baseline levels of target detection between the groups into closer alignment. We found that the integration dysfunction rather than deployment of attention is clinically relevant, and thus should be an additional focus of research in schizophrenia.
| Original language | English (US) |
|---|---|
| Article number | 9745 |
| Journal | Scientific reports |
| Volume | 5 |
| DOIs | |
| State | Published - May 5 2015 |
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All Science Journal Classification (ASJC) codes
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Temporal perception deficits in schizophrenia : Integration is the problem, not deployment of attentions. / Su, Li; Wyble, Brad; Zhou, Lai Quan; Wang, Kui; Wang, Yu Na; Cheung, Eric F.C.; Bowman, Howard; Chan, Raymond C.K.
In: Scientific reports, Vol. 5, 9745, 05.05.2015.Research output: Contribution to journal › Article
TY - JOUR
T1 - Temporal perception deficits in schizophrenia
T2 - Integration is the problem, not deployment of attentions
AU - Su, Li
AU - Wyble, Brad
AU - Zhou, Lai Quan
AU - Wang, Kui
AU - Wang, Yu Na
AU - Cheung, Eric F.C.
AU - Bowman, Howard
AU - Chan, Raymond C.K.
PY - 2015/5/5
Y1 - 2015/5/5
N2 - Patients with schizophrenia are known to have impairments in sensory processing. In order to understand the specific temporal perception deficits of schizophrenia, we investigated and determined to what extent impairments in temporal integration can be dissociated from attention deployment using Attentional Blink (AB). Our findings showed that there was no evident deficit in the deployment of attention in patients with schizophrenia. However, patients showed an increased temporal integration deficit within a hundred-millisecond timescale. The degree of such integration dysfunction was correlated with the clinical manifestations of schizophrenia. There was no difference between individuals with/without schizotypal personality disorder in temporal integration. Differently from previous studies using the AB, we did not find a significant impairment in deployment of attention in schizophrenia. Instead, we used both theoretical and empirical approaches to show that previous findings (using the suppression ratio to correct for the baseline difference) produced a systematic exaggeration of the attention deficits. Instead, we modulated the perceptual difficulty of the task to bring the baseline levels of target detection between the groups into closer alignment. We found that the integration dysfunction rather than deployment of attention is clinically relevant, and thus should be an additional focus of research in schizophrenia.
AB - Patients with schizophrenia are known to have impairments in sensory processing. In order to understand the specific temporal perception deficits of schizophrenia, we investigated and determined to what extent impairments in temporal integration can be dissociated from attention deployment using Attentional Blink (AB). Our findings showed that there was no evident deficit in the deployment of attention in patients with schizophrenia. However, patients showed an increased temporal integration deficit within a hundred-millisecond timescale. The degree of such integration dysfunction was correlated with the clinical manifestations of schizophrenia. There was no difference between individuals with/without schizotypal personality disorder in temporal integration. Differently from previous studies using the AB, we did not find a significant impairment in deployment of attention in schizophrenia. Instead, we used both theoretical and empirical approaches to show that previous findings (using the suppression ratio to correct for the baseline difference) produced a systematic exaggeration of the attention deficits. Instead, we modulated the perceptual difficulty of the task to bring the baseline levels of target detection between the groups into closer alignment. We found that the integration dysfunction rather than deployment of attention is clinically relevant, and thus should be an additional focus of research in schizophrenia.
UR - http://www.scopus.com/inward/record.url?scp=84929153887&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929153887&partnerID=8YFLogxK
U2 - 10.1038/srep09745
DO - 10.1038/srep09745
M3 - Article
C2 - 25940093
AN - SCOPUS:84929153887
VL - 5
JO - Scientific Reports
JF - Scientific Reports
SN - 2045-2322
M1 - 9745
ER -