@article{70bc007acf604541b8add927a94184b6,
title = "Temporal perception deficits in schizophrenia: Integration is the problem, not deployment of attentions",
abstract = "Patients with schizophrenia are known to have impairments in sensory processing. In order to understand the specific temporal perception deficits of schizophrenia, we investigated and determined to what extent impairments in temporal integration can be dissociated from attention deployment using Attentional Blink (AB). Our findings showed that there was no evident deficit in the deployment of attention in patients with schizophrenia. However, patients showed an increased temporal integration deficit within a hundred-millisecond timescale. The degree of such integration dysfunction was correlated with the clinical manifestations of schizophrenia. There was no difference between individuals with/without schizotypal personality disorder in temporal integration. Differently from previous studies using the AB, we did not find a significant impairment in deployment of attention in schizophrenia. Instead, we used both theoretical and empirical approaches to show that previous findings (using the suppression ratio to correct for the baseline difference) produced a systematic exaggeration of the attention deficits. Instead, we modulated the perceptual difficulty of the task to bring the baseline levels of target detection between the groups into closer alignment. We found that the integration dysfunction rather than deployment of attention is clinically relevant, and thus should be an additional focus of research in schizophrenia.",
author = "Li Su and Brad Wyble and Zhou, {Lai Quan} and Kui Wang and Wang, {Yu Na} and Cheung, {Eric F.C.} and Howard Bowman and Chan, {Raymond C.K.}",
note = "Funding Information: This research was supported by an open competitive grant of the Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences to LS; LS is also supported by the NIHR Biomedical Research Centre and Biomedical Research Unit in Dementia based at Cambridge University Hospitals NHS Foundation Trust; the involvement of RCKC was supported by the National Science Fund China Young Investigator Award (81088001), and the Knowledge Innovation Project of the Chinese Academy of Sciences (KSCX2-EW-J-8), and the Key Laboratory of Mental Health, Institute of Psychology. These funding agents had no role in the study design; collection, analysis, and interpretation of the data; writing of the manuscript; or decision to submit the paper for publication. We thank Axel Cleeremans for discussions on episodic distinctiveness, and Richard D. Morey for discussions on Bayesian inference. Funding Information: LS designed the experiment, analyzed the data and wrote the manuscript; BW co-designed the experiment and commented on the manuscript; LQZ, KW and YNW collected the demographic, clinical and behavioral data and processed the data; EFCC commented on the manuscript; HB and RCKC codesigned the experiment and commented on the manuscript. LS and RCKC obtained the financial support and oversaw the study.",
year = "2015",
month = may,
day = "5",
doi = "10.1038/srep09745",
language = "English (US)",
volume = "5",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
}