Teratogenicity of ethanol in different chicken strains

Stephanie R. Bupp Becker, Ivan A. Shibley

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

This study investigated the teratogenicity of ethanol in several different strains of chickens. The chick embryo provides a useful model for studying the fetal alcohol syndrome. Two broad classifications of chicks, each containing many strains, are commercially available for use: broilers and layers. Teratogenicity of ethanol in broilers and layers was studied by examining three different parameters: embryo weight, ratio of torso weight to head weight, and embryo viability. Broilers and layers experienced similar ethanol-induced reductions in embryo weight. Broiler embryos experienced a preferential ethanol-induced suppression of head growth. Differences in viability between different strains were found, but no clear pattern between broilers or layers could be determined, possibly due to environmental conditions. The data presented here suggest that the strain of chick and the handling of the eggs are important considerations when studying the teratogenicity of ethanol. An ethanol dose-response test should be periodically performed as a check on environmental conditions affecting the eggs conditions that are beyond the control of the researcher.

Original languageEnglish (US)
Pages (from-to)457-464
Number of pages8
JournalAlcohol and Alcoholism
Volume33
Issue number5
DOIs
StatePublished - Sep 1 1998

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

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