Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores

T. J.A. Key, L. Roe, M. Thorogood, J. W. Moore, G. M.G. Clark, D. Y. Wang

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Total testosterone (T), total oestradiol (E2) and sex hormone-binding globulin (SHBG) concentrations were measured in plasma samples from fifty-one male vegans and fifty-seven omnivores of similar age. Free T concentration was estimated by calculation. In comparison with the omnivores, the vegans had 7% higher total T (P = 0.250), 23% higher SHBG (P = 0.001), 3% lower free T (P = 0.580), and 11% higher E2 (P = 0.194). In a subset of eighteen vegans and twenty-two omnivores for whom 4 diet records were available, there were statistically significant correlations between T and polyunsaturated fatty acids (r 0.37), SHBG and fat (r 0.43 for total fat, 0.46 for saturated fatty acids and 0.33 for polyunsaturated fatty acids), and SHBG and alcohol (r - 0.39). It is concluded that a vegan diet causes a substantial increase in SHBG but has little effect on total or free T or on E2.

Original languageEnglish (US)
Pages (from-to)111-119
Number of pages9
JournalBritish Journal of Nutrition
Volume64
Issue number1
DOIs
StatePublished - Sep 14 1990

Fingerprint

Sex Hormone-Binding Globulin
Testosterone
Estradiol
Unsaturated Fatty Acids
Fats
Diet Records
Fatty Acids
Alcohols
Vegans

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Key, T. J.A. ; Roe, L. ; Thorogood, M. ; Moore, J. W. ; Clark, G. M.G. ; Wang, D. Y. / Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores. In: British Journal of Nutrition. 1990 ; Vol. 64, No. 1. pp. 111-119.
@article{59471628e5754eda83a096fafe98a971,
title = "Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores",
abstract = "Total testosterone (T), total oestradiol (E2) and sex hormone-binding globulin (SHBG) concentrations were measured in plasma samples from fifty-one male vegans and fifty-seven omnivores of similar age. Free T concentration was estimated by calculation. In comparison with the omnivores, the vegans had 7{\%} higher total T (P = 0.250), 23{\%} higher SHBG (P = 0.001), 3{\%} lower free T (P = 0.580), and 11{\%} higher E2 (P = 0.194). In a subset of eighteen vegans and twenty-two omnivores for whom 4 diet records were available, there were statistically significant correlations between T and polyunsaturated fatty acids (r 0.37), SHBG and fat (r 0.43 for total fat, 0.46 for saturated fatty acids and 0.33 for polyunsaturated fatty acids), and SHBG and alcohol (r - 0.39). It is concluded that a vegan diet causes a substantial increase in SHBG but has little effect on total or free T or on E2.",
author = "Key, {T. J.A.} and L. Roe and M. Thorogood and Moore, {J. W.} and Clark, {G. M.G.} and Wang, {D. Y.}",
year = "1990",
month = "9",
day = "14",
doi = "10.1079/BJN19900014",
language = "English (US)",
volume = "64",
pages = "111--119",
journal = "British Journal of Nutrition",
issn = "0007-1145",
publisher = "Cambridge University Press",
number = "1",

}

Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores. / Key, T. J.A.; Roe, L.; Thorogood, M.; Moore, J. W.; Clark, G. M.G.; Wang, D. Y.

In: British Journal of Nutrition, Vol. 64, No. 1, 14.09.1990, p. 111-119.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Testosterone, sex hormone-binding globulin, calculated free testosterone, and oestradiol in male vegans and omnivores

AU - Key, T. J.A.

AU - Roe, L.

AU - Thorogood, M.

AU - Moore, J. W.

AU - Clark, G. M.G.

AU - Wang, D. Y.

PY - 1990/9/14

Y1 - 1990/9/14

N2 - Total testosterone (T), total oestradiol (E2) and sex hormone-binding globulin (SHBG) concentrations were measured in plasma samples from fifty-one male vegans and fifty-seven omnivores of similar age. Free T concentration was estimated by calculation. In comparison with the omnivores, the vegans had 7% higher total T (P = 0.250), 23% higher SHBG (P = 0.001), 3% lower free T (P = 0.580), and 11% higher E2 (P = 0.194). In a subset of eighteen vegans and twenty-two omnivores for whom 4 diet records were available, there were statistically significant correlations between T and polyunsaturated fatty acids (r 0.37), SHBG and fat (r 0.43 for total fat, 0.46 for saturated fatty acids and 0.33 for polyunsaturated fatty acids), and SHBG and alcohol (r - 0.39). It is concluded that a vegan diet causes a substantial increase in SHBG but has little effect on total or free T or on E2.

AB - Total testosterone (T), total oestradiol (E2) and sex hormone-binding globulin (SHBG) concentrations were measured in plasma samples from fifty-one male vegans and fifty-seven omnivores of similar age. Free T concentration was estimated by calculation. In comparison with the omnivores, the vegans had 7% higher total T (P = 0.250), 23% higher SHBG (P = 0.001), 3% lower free T (P = 0.580), and 11% higher E2 (P = 0.194). In a subset of eighteen vegans and twenty-two omnivores for whom 4 diet records were available, there were statistically significant correlations between T and polyunsaturated fatty acids (r 0.37), SHBG and fat (r 0.43 for total fat, 0.46 for saturated fatty acids and 0.33 for polyunsaturated fatty acids), and SHBG and alcohol (r - 0.39). It is concluded that a vegan diet causes a substantial increase in SHBG but has little effect on total or free T or on E2.

UR - http://www.scopus.com/inward/record.url?scp=0025108760&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025108760&partnerID=8YFLogxK

U2 - 10.1079/BJN19900014

DO - 10.1079/BJN19900014

M3 - Article

C2 - 2400756

AN - SCOPUS:0025108760

VL - 64

SP - 111

EP - 119

JO - British Journal of Nutrition

JF - British Journal of Nutrition

SN - 0007-1145

IS - 1

ER -