The added benefit of a dedicated neck F-18 FDG PET-CT imaging protocol in patients with suspected recurrent differentiated thyroid carcinoma

Jonathan M. Davison, Derek J. Stocker, Jaime L. Montilla-Soler, Jennifer S. Jurgens, Thomas W. Allen, Timothy S. Holley, Aaron L. Stack

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

PURPOSE: To retrospectively analyze whether adding a delayed high-resolution dedicated neck F-18 FDG positron emission tomography- computerized tomographic (PET-CT) imaging protocol in patients with recurrent differentiated thyroid cancer increases the number of abnormal foci within the neck. MATERIALS AND METHODS: Seventeen PET-CT studies from a total of 10 patients with suspected recurrent differentiated thyroid cancer between March 2003 and June 2004 were retrospectively reviewed. Each study included a whole body acquisition (WBA), followed by higher resolution dedicated neck acquisition (DNA). Two board-certified nuclear medicine physicians reviewed either the DNA or WBA for each study and recorded the number of abnormal foci, along with presence or absence of a soft tissue abnormality, and maximum standardized uptake value for each foci. Consensus review was used for all discrepancies. Statistical analysis was performed to determine whether there was a statistically significant increase in the number of studies demonstrating new abnormal foci with the addition of a DNA. RESULTS: Five of 17 studies demonstrated an increase in the number of abnormal foci with the addition of the DNA (P < 0.04). A total of 8 abnormal foci were noted on the WBA, 4 of which were within the neck. Eleven additional abnormal foci were seen on the DNA. All abnormal foci within the neck had corresponding soft tissue abnormalities except for one. CONCLUSION: Adding a higher resolution delayed DNA to the WBA for patients undergoing PET-CT imaging to detect recurrent thyroid cancer increases the number of abnormal sites of FDG accumulation.

Original languageEnglish (US)
Pages (from-to)464-468
Number of pages5
JournalClinical nuclear medicine
Volume33
Issue number7
DOIs
StatePublished - Jul 1 2008

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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