The biggest winners in DNA and protein sequence analysis: Metagenomics, DNA microarray, biosensors, molecular subtyping, and phage recombinant probes

Sufian F. Al-Khaldi, Magdi M. Mossoba, Betsy Jean Yakes, Eric Wayne Brown, Devang Sharma, Santina Carnazza

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In an age of molecular genetics, viable but not culturable organisms, and highly sophisticated DNA sequence analysis technologies, is there a chance for a new breakthrough? It is quite extraordinary that 99% of microorganisms not only can't be cultured but are totally unknown to the scientific community. Many bacterial gene functions and identifications in the environment have been uncovered by recent advances in metagenomics or culture-independent genomic analysis in addition to the DNA microarray technology. Our knowledge of detecting and classifying bacterial isolates has been also improved by cutting-edge molecular tools such as biosensors and molecular subtyping as well as phage recombinant probes. Microbial communities, many to be discovered, are slowly revealed by these sharp scientific discoveries.

Original languageEnglish (US)
Title of host publicationDNA Research, Genetics and Cell Biology
PublisherNova Science Publishers, Inc.
Pages61-86
Number of pages26
ISBN (Print)9781611227925
StatePublished - Dec 1 2011

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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    Al-Khaldi, S. F., Mossoba, M. M., Yakes, B. J., Brown, E. W., Sharma, D., & Carnazza, S. (2011). The biggest winners in DNA and protein sequence analysis: Metagenomics, DNA microarray, biosensors, molecular subtyping, and phage recombinant probes. In DNA Research, Genetics and Cell Biology (pp. 61-86). Nova Science Publishers, Inc..