The decline of malaria in Vietnam, 1991-2014

Sandra M. Goldlust, Phung Duc Thuan, Dang Duy Hoang Giang, Ngo Duc Thang, Guy E. Thwaites, Jeremy Farrar, Ngo Viet Thanh, Tran Dang Nguyen, Bryan T. Grenfell, Maciej F. Boni, Tran Tinh Hien

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: Despite the well-documented clinical efficacy of artemisinin-based combination therapy (ACT) against malaria, the population-level effects of ACT have not been studied thoroughly until recently. An ideal case study for these population-level effects can be found in Vietnam's gradual adoption of artemisinin in the 1990s. Methods and results: Analysis of Vietnam's national annual malaria reports (1991-2014) revealed that a 10% increase in artemisinin procurement corresponded to a 32.8% (95% CI 27.7-37.5%) decline in estimated malaria cases. There was no consistent national or regional effect of vector control on malaria. The association between urbanization and malaria was generally negative and sometimes statistically significant. Conclusions: The decline of malaria in Vietnam can largely be attributed to the adoption of artemisinin-based case management. Recent analyses from Africa showed that insecticide-treated nets had the greatest effect on lowering malaria prevalence, suggesting that the success of interventions is region-specific. Continuing malaria elimination efforts should focus on both vector control and increased access to ACT.

Original languageEnglish (US)
Article number226
JournalMalaria journal
Volume17
Issue number1
DOIs
StatePublished - Jun 7 2018

Fingerprint

Vietnam
Malaria
Annual Reports
Urbanization
Case Management
Insecticides
Population
artemisinine
Therapeutics

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Infectious Diseases

Cite this

Goldlust, S. M., Thuan, P. D., Giang, D. D. H., Thang, N. D., Thwaites, G. E., Farrar, J., ... Hien, T. T. (2018). The decline of malaria in Vietnam, 1991-2014. Malaria journal, 17(1), [226]. https://doi.org/10.1186/s12936-018-2372-8
Goldlust, Sandra M. ; Thuan, Phung Duc ; Giang, Dang Duy Hoang ; Thang, Ngo Duc ; Thwaites, Guy E. ; Farrar, Jeremy ; Thanh, Ngo Viet ; Nguyen, Tran Dang ; Grenfell, Bryan T. ; Boni, Maciej F. ; Hien, Tran Tinh. / The decline of malaria in Vietnam, 1991-2014. In: Malaria journal. 2018 ; Vol. 17, No. 1.
@article{fa5572fe21dd479099e4464083fe483f,
title = "The decline of malaria in Vietnam, 1991-2014",
abstract = "Background: Despite the well-documented clinical efficacy of artemisinin-based combination therapy (ACT) against malaria, the population-level effects of ACT have not been studied thoroughly until recently. An ideal case study for these population-level effects can be found in Vietnam's gradual adoption of artemisinin in the 1990s. Methods and results: Analysis of Vietnam's national annual malaria reports (1991-2014) revealed that a 10{\%} increase in artemisinin procurement corresponded to a 32.8{\%} (95{\%} CI 27.7-37.5{\%}) decline in estimated malaria cases. There was no consistent national or regional effect of vector control on malaria. The association between urbanization and malaria was generally negative and sometimes statistically significant. Conclusions: The decline of malaria in Vietnam can largely be attributed to the adoption of artemisinin-based case management. Recent analyses from Africa showed that insecticide-treated nets had the greatest effect on lowering malaria prevalence, suggesting that the success of interventions is region-specific. Continuing malaria elimination efforts should focus on both vector control and increased access to ACT.",
author = "Goldlust, {Sandra M.} and Thuan, {Phung Duc} and Giang, {Dang Duy Hoang} and Thang, {Ngo Duc} and Thwaites, {Guy E.} and Jeremy Farrar and Thanh, {Ngo Viet} and Nguyen, {Tran Dang} and Grenfell, {Bryan T.} and Boni, {Maciej F.} and Hien, {Tran Tinh}",
year = "2018",
month = "6",
day = "7",
doi = "10.1186/s12936-018-2372-8",
language = "English (US)",
volume = "17",
journal = "Malaria Journal",
issn = "1475-2875",
publisher = "BioMed Central",
number = "1",

}

Goldlust, SM, Thuan, PD, Giang, DDH, Thang, ND, Thwaites, GE, Farrar, J, Thanh, NV, Nguyen, TD, Grenfell, BT, Boni, MF & Hien, TT 2018, 'The decline of malaria in Vietnam, 1991-2014', Malaria journal, vol. 17, no. 1, 226. https://doi.org/10.1186/s12936-018-2372-8

The decline of malaria in Vietnam, 1991-2014. / Goldlust, Sandra M.; Thuan, Phung Duc; Giang, Dang Duy Hoang; Thang, Ngo Duc; Thwaites, Guy E.; Farrar, Jeremy; Thanh, Ngo Viet; Nguyen, Tran Dang; Grenfell, Bryan T.; Boni, Maciej F.; Hien, Tran Tinh.

In: Malaria journal, Vol. 17, No. 1, 226, 07.06.2018.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The decline of malaria in Vietnam, 1991-2014

AU - Goldlust, Sandra M.

AU - Thuan, Phung Duc

AU - Giang, Dang Duy Hoang

AU - Thang, Ngo Duc

AU - Thwaites, Guy E.

AU - Farrar, Jeremy

AU - Thanh, Ngo Viet

AU - Nguyen, Tran Dang

AU - Grenfell, Bryan T.

AU - Boni, Maciej F.

AU - Hien, Tran Tinh

PY - 2018/6/7

Y1 - 2018/6/7

N2 - Background: Despite the well-documented clinical efficacy of artemisinin-based combination therapy (ACT) against malaria, the population-level effects of ACT have not been studied thoroughly until recently. An ideal case study for these population-level effects can be found in Vietnam's gradual adoption of artemisinin in the 1990s. Methods and results: Analysis of Vietnam's national annual malaria reports (1991-2014) revealed that a 10% increase in artemisinin procurement corresponded to a 32.8% (95% CI 27.7-37.5%) decline in estimated malaria cases. There was no consistent national or regional effect of vector control on malaria. The association between urbanization and malaria was generally negative and sometimes statistically significant. Conclusions: The decline of malaria in Vietnam can largely be attributed to the adoption of artemisinin-based case management. Recent analyses from Africa showed that insecticide-treated nets had the greatest effect on lowering malaria prevalence, suggesting that the success of interventions is region-specific. Continuing malaria elimination efforts should focus on both vector control and increased access to ACT.

AB - Background: Despite the well-documented clinical efficacy of artemisinin-based combination therapy (ACT) against malaria, the population-level effects of ACT have not been studied thoroughly until recently. An ideal case study for these population-level effects can be found in Vietnam's gradual adoption of artemisinin in the 1990s. Methods and results: Analysis of Vietnam's national annual malaria reports (1991-2014) revealed that a 10% increase in artemisinin procurement corresponded to a 32.8% (95% CI 27.7-37.5%) decline in estimated malaria cases. There was no consistent national or regional effect of vector control on malaria. The association between urbanization and malaria was generally negative and sometimes statistically significant. Conclusions: The decline of malaria in Vietnam can largely be attributed to the adoption of artemisinin-based case management. Recent analyses from Africa showed that insecticide-treated nets had the greatest effect on lowering malaria prevalence, suggesting that the success of interventions is region-specific. Continuing malaria elimination efforts should focus on both vector control and increased access to ACT.

UR - http://www.scopus.com/inward/record.url?scp=85048085427&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85048085427&partnerID=8YFLogxK

U2 - 10.1186/s12936-018-2372-8

DO - 10.1186/s12936-018-2372-8

M3 - Article

C2 - 29880051

AN - SCOPUS:85048085427

VL - 17

JO - Malaria Journal

JF - Malaria Journal

SN - 1475-2875

IS - 1

M1 - 226

ER -

Goldlust SM, Thuan PD, Giang DDH, Thang ND, Thwaites GE, Farrar J et al. The decline of malaria in Vietnam, 1991-2014. Malaria journal. 2018 Jun 7;17(1). 226. https://doi.org/10.1186/s12936-018-2372-8