The diameter of melanomas

Emmy M. Fernandez, Klaus Helm

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

BACKGROUND. The mnemonic ABCD, which stands for asymmetry, border irregularity, color variation, and diameter greater than 6 mm alerts physicians to features that suggest melanoma. Although the ABCD criteria are guidelines for diagnosis, clinicians may overlook many melanomas that do not follow the ABCD rule. OBJECTIVE. We examined the sensitivity of the diameter portion of the ABCD rule. METHODS. Retrospective study examining the pathology reports of 383 melanomas. Data were compiled for each melanoma regarding its diameter, depth, body location, patient age, and sex. A 95% confidence interval (p = 0.05) was used to identify the proportion of melanomas less than or equal to 6 mm in diameter. A two-tailed p value approach (p value = 0.05, degrees of freedom = 28) was used when evaluating two independent populations, lesions less than or equal to 6 mm and lesions greater than 6 mm in diameter. RESULTS. A total of 38.21% of melanomas were less than or equal to 6 mm in diameter after processing. Melanomas greater than 6 mm in diameter occurred in significantly older patients and at a greater Breslow's thickness than smaller melanomas. CONCLUSIONS. We demonstrated that a significant proportion of melanomas may be smaller than 6 mm. The ABCD criteria are not absolute; melanomas have many different appearances and start as small lesions.

Original languageEnglish (US)
Pages (from-to)1219-1222
Number of pages4
JournalDermatologic Surgery
Volume30
Issue number9
DOIs
StatePublished - Sep 1 2004

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Melanoma
Retrospective Studies
Color
Guidelines
Confidence Intervals
Pathology
Physicians
Population

All Science Journal Classification (ASJC) codes

  • Surgery
  • Dermatology

Cite this

Fernandez, Emmy M. ; Helm, Klaus. / The diameter of melanomas. In: Dermatologic Surgery. 2004 ; Vol. 30, No. 9. pp. 1219-1222.
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The diameter of melanomas. / Fernandez, Emmy M.; Helm, Klaus.

In: Dermatologic Surgery, Vol. 30, No. 9, 01.09.2004, p. 1219-1222.

Research output: Contribution to journalArticle

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N2 - BACKGROUND. The mnemonic ABCD, which stands for asymmetry, border irregularity, color variation, and diameter greater than 6 mm alerts physicians to features that suggest melanoma. Although the ABCD criteria are guidelines for diagnosis, clinicians may overlook many melanomas that do not follow the ABCD rule. OBJECTIVE. We examined the sensitivity of the diameter portion of the ABCD rule. METHODS. Retrospective study examining the pathology reports of 383 melanomas. Data were compiled for each melanoma regarding its diameter, depth, body location, patient age, and sex. A 95% confidence interval (p = 0.05) was used to identify the proportion of melanomas less than or equal to 6 mm in diameter. A two-tailed p value approach (p value = 0.05, degrees of freedom = 28) was used when evaluating two independent populations, lesions less than or equal to 6 mm and lesions greater than 6 mm in diameter. RESULTS. A total of 38.21% of melanomas were less than or equal to 6 mm in diameter after processing. Melanomas greater than 6 mm in diameter occurred in significantly older patients and at a greater Breslow's thickness than smaller melanomas. CONCLUSIONS. We demonstrated that a significant proportion of melanomas may be smaller than 6 mm. The ABCD criteria are not absolute; melanomas have many different appearances and start as small lesions.

AB - BACKGROUND. The mnemonic ABCD, which stands for asymmetry, border irregularity, color variation, and diameter greater than 6 mm alerts physicians to features that suggest melanoma. Although the ABCD criteria are guidelines for diagnosis, clinicians may overlook many melanomas that do not follow the ABCD rule. OBJECTIVE. We examined the sensitivity of the diameter portion of the ABCD rule. METHODS. Retrospective study examining the pathology reports of 383 melanomas. Data were compiled for each melanoma regarding its diameter, depth, body location, patient age, and sex. A 95% confidence interval (p = 0.05) was used to identify the proportion of melanomas less than or equal to 6 mm in diameter. A two-tailed p value approach (p value = 0.05, degrees of freedom = 28) was used when evaluating two independent populations, lesions less than or equal to 6 mm and lesions greater than 6 mm in diameter. RESULTS. A total of 38.21% of melanomas were less than or equal to 6 mm in diameter after processing. Melanomas greater than 6 mm in diameter occurred in significantly older patients and at a greater Breslow's thickness than smaller melanomas. CONCLUSIONS. We demonstrated that a significant proportion of melanomas may be smaller than 6 mm. The ABCD criteria are not absolute; melanomas have many different appearances and start as small lesions.

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