The effect of cell shape on local hydrodynamic environment

Yi Fu, Ying Fang, Jianhua Wu, Cheng Dong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cell adhesion is very important for various biological phenomena in blood flow. Cells would deform to resist the hydrodynamic forces on the blood vessel wall, which results in local flow environment change due to the disturbance of adherent cells. In this paper, computational fluid dynamics simulations were performed to investigate the effect of cell shape on local hydrodynamic environment in details. We found that under a flow condition 73 l/min, cell shape would more affect the flow in one cell height region. Moreover, cell length, the position of cell top and cell shape curvature may also affect the local hydrodynamic environment as well as the drag forces differently.

Original languageEnglish (US)
Title of host publicationITME 2011 - Proceedings
Subtitle of host publication2011 IEEE International Symposium on IT in Medicine and Education
Pages540-543
Number of pages4
DOIs
StatePublished - Dec 1 2011
Event2011 IEEE International Symposium on IT in Medicine and Education, ITME 2011 - Guangzhou, China
Duration: Dec 9 2011Dec 11 2011

Publication series

NameITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education
Volume1

Other

Other2011 IEEE International Symposium on IT in Medicine and Education, ITME 2011
CountryChina
CityGuangzhou
Period12/9/1112/11/11

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All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Biomedical Engineering
  • Education

Cite this

Fu, Y., Fang, Y., Wu, J., & Dong, C. (2011). The effect of cell shape on local hydrodynamic environment. In ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education (pp. 540-543). [6130895] (ITME 2011 - Proceedings: 2011 IEEE International Symposium on IT in Medicine and Education; Vol. 1). https://doi.org/10.1109/ITiME.2011.6130895