The effect of hydrogel nucleus implant on the mechanical behavior of the lumbar functional spinal unit: An experimental study

A. Joshi, E. Vresilovic, M. Marcolongo, A. Lowman, A. Karduna

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Over five million Americans suffer from lower back pain, making it the leading cause of lost workdays in the United States. The origin of the low back pain is often the degenerated lumbar intervertebral disc. Current treatment options such as discectomy and/or spinal fusion fail to restore normal biomechanics of the spine. We are investing replacing the nucleus pulposus of the intervertebral disc with polymeric hydrogel implant. The present study reports the effect of polymeric hydrogel implant on the mechanical behavior of the human cadaveric lumbar functional spinal unit in axial compression. The implantation of the hydrogel implant in the denucleated specimen significantly restores the compressive behavior of the functional spinal unit. This implantation of a hydrogel nucleus replacement shows promise in restoring the normal biomechanics of the spine.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE 29th Annual Northeast Bioengineering Conference
EditorsStanley Reisman, Richard Foulds, Bruno Mantilla
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages211-212
Number of pages2
ISBN (Electronic)0780377672
DOIs
StatePublished - Jan 1 2003
Event29th IEEE Annual Northeast Bioengineering Conference, NEBC 2003 - Newark, United States
Duration: Mar 22 2003Mar 23 2003

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
Volume2003-January
ISSN (Print)1071-121X
ISSN (Electronic)2160-7001

Other

Other29th IEEE Annual Northeast Bioengineering Conference, NEBC 2003
CountryUnited States
CityNewark
Period3/22/033/23/03

Fingerprint

Hydrogel
Hydrogels
Biomechanics
Axial compression
Fusion reactions

All Science Journal Classification (ASJC) codes

  • Bioengineering

Cite this

Joshi, A., Vresilovic, E., Marcolongo, M., Lowman, A., & Karduna, A. (2003). The effect of hydrogel nucleus implant on the mechanical behavior of the lumbar functional spinal unit: An experimental study. In S. Reisman, R. Foulds, & B. Mantilla (Eds.), Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference (pp. 211-212). [1216068] (Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC; Vol. 2003-January). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEBC.2003.1216068
Joshi, A. ; Vresilovic, E. ; Marcolongo, M. ; Lowman, A. ; Karduna, A. / The effect of hydrogel nucleus implant on the mechanical behavior of the lumbar functional spinal unit : An experimental study. Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference. editor / Stanley Reisman ; Richard Foulds ; Bruno Mantilla. Institute of Electrical and Electronics Engineers Inc., 2003. pp. 211-212 (Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC).
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Joshi, A, Vresilovic, E, Marcolongo, M, Lowman, A & Karduna, A 2003, The effect of hydrogel nucleus implant on the mechanical behavior of the lumbar functional spinal unit: An experimental study. in S Reisman, R Foulds & B Mantilla (eds), Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference., 1216068, Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC, vol. 2003-January, Institute of Electrical and Electronics Engineers Inc., pp. 211-212, 29th IEEE Annual Northeast Bioengineering Conference, NEBC 2003, Newark, United States, 3/22/03. https://doi.org/10.1109/NEBC.2003.1216068

The effect of hydrogel nucleus implant on the mechanical behavior of the lumbar functional spinal unit : An experimental study. / Joshi, A.; Vresilovic, E.; Marcolongo, M.; Lowman, A.; Karduna, A.

Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference. ed. / Stanley Reisman; Richard Foulds; Bruno Mantilla. Institute of Electrical and Electronics Engineers Inc., 2003. p. 211-212 1216068 (Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC; Vol. 2003-January).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Joshi A, Vresilovic E, Marcolongo M, Lowman A, Karduna A. The effect of hydrogel nucleus implant on the mechanical behavior of the lumbar functional spinal unit: An experimental study. In Reisman S, Foulds R, Mantilla B, editors, Proceedings of the IEEE 29th Annual Northeast Bioengineering Conference. Institute of Electrical and Electronics Engineers Inc. 2003. p. 211-212. 1216068. (Proceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC). https://doi.org/10.1109/NEBC.2003.1216068