The effect of hypercholestrolemia on calf muscle hemoglobin oxygen saturation in patients with intermittent claudication

Azhar Afaq, Polly S. Montgomery, Kristy J. Scott, Steve M. Blevins, Thomas L. Whitsett, Andrew Gardner

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The purpose was to compare calf muscle hemoglobin oxygen saturation and exercise performance in hypercholesterolemic and normocholesterolemic patients with peripheral arterial disease. Hypercholesterolemic and normocholesterolemic patients had similar ankle/ brachial index (0.72 ± 0.24 vs 0.79 ± 0.28, [mean ± SD]; P =.334). Hypercholesterolemic patients had shorter initial claudication distance (214 ± 168 m vs 331 ± 185 m, P =.026), absolute claudication distance (391 ± 219 m vs 549 ± 211 m, P =.035), and lower calf muscle hemoglobin oxygen saturation at the occurrence of initial claudication distance (27 ± 21% vs 39 ± 20%; P =.013), and absolute claudication distance (26 ± 21% vs 36 ± 21%; P =.021). Hypercholesterolemia is associated with shorter walking distances and calf muscle hemoglobin oxygen saturation during exercise in patients limited by intermittent claudication.

Original languageEnglish (US)
Pages (from-to)534-541
Number of pages8
JournalAngiology
Volume59
Issue number5
DOIs
StatePublished - Oct 1 2008

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Intermittent Claudication
Hemoglobins
Oxygen
Muscles
Exercise
Ankle Brachial Index
Peripheral Arterial Disease
Hypercholesterolemia
Walking

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Afaq, Azhar ; Montgomery, Polly S. ; Scott, Kristy J. ; Blevins, Steve M. ; Whitsett, Thomas L. ; Gardner, Andrew. / The effect of hypercholestrolemia on calf muscle hemoglobin oxygen saturation in patients with intermittent claudication. In: Angiology. 2008 ; Vol. 59, No. 5. pp. 534-541.
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The effect of hypercholestrolemia on calf muscle hemoglobin oxygen saturation in patients with intermittent claudication. / Afaq, Azhar; Montgomery, Polly S.; Scott, Kristy J.; Blevins, Steve M.; Whitsett, Thomas L.; Gardner, Andrew.

In: Angiology, Vol. 59, No. 5, 01.10.2008, p. 534-541.

Research output: Contribution to journalArticle

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