Abstract
The purpose was to compare calf muscle hemoglobin oxygen saturation and exercise performance in hypercholesterolemic and normocholesterolemic patients with peripheral arterial disease. Hypercholesterolemic and normocholesterolemic patients had similar ankle/ brachial index (0.72 ± 0.24 vs 0.79 ± 0.28, [mean ± SD]; P =.334). Hypercholesterolemic patients had shorter initial claudication distance (214 ± 168 m vs 331 ± 185 m, P =.026), absolute claudication distance (391 ± 219 m vs 549 ± 211 m, P =.035), and lower calf muscle hemoglobin oxygen saturation at the occurrence of initial claudication distance (27 ± 21% vs 39 ± 20%; P =.013), and absolute claudication distance (26 ± 21% vs 36 ± 21%; P =.021). Hypercholesterolemia is associated with shorter walking distances and calf muscle hemoglobin oxygen saturation during exercise in patients limited by intermittent claudication.
Original language | English (US) |
---|---|
Pages (from-to) | 534-541 |
Number of pages | 8 |
Journal | Angiology |
Volume | 59 |
Issue number | 5 |
DOIs | |
State | Published - Oct 2008 |
All Science Journal Classification (ASJC) codes
- Cardiology and Cardiovascular Medicine