The effect of nucleus implant parameters on the compressive mechanics of the lumbar intervertebral disc: A finite element study

Abhijeet Joshi, Christopher J. Massey, Andrew Karduna, Edward Vresilovic, Michele Marcolongo

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

A simplified finite element model of the human lumbar intervertebral disc was utilized for understanding nucleus pulposus implant mechanics. The model was used to assess the effect of nucleus implant parameter variations on the resulting compressive biomechanics of the lumbar anterior column unit. The effects of nucleus implant material (modulus and Poisson's ratio) and geometrical (height and diameter) parameters on the mechanical behavior of the disc were investigated. The model predicted that variations in implant modulus contribute less to the compressive disc mechanics compared to the implant geometrical parameters, for the ranges examined. It was concluded that some threshold exists for the nucleus implant modulus, below which little variations in load-displacement behavior were shown. Compressive biomechanics were highly affected by implant volume (under-filling the nucleus cavity, line-to-line fit, or over-filling the nucleus cavity) with a greater restoration of compressive mechanics observed with the over-filled implant design. This work indicated the effect of nucleus implant parameter variations on the compressive mechanics of the human lumbar intervertebral disc and importance of the "fit and fill" effect of the nuclear cavity in the restoration of the human intervertebral disc mechanics in compression. These findings may have clinical significance for nucleus implant design.

Original languageEnglish (US)
Pages (from-to)596-607
Number of pages12
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume90 B
Issue number2
DOIs
StatePublished - Aug 2009

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering

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