Overwhelming postsplenectomy infection is a widely discussed and studied problem. The route of infection, the specific organisms involved, and the age at splenectomy and bacterial challenge are crucial factors in determining the genuine threat of the disease. The authors studied Staphylococcus aureus respiratory infection in 10-day-old mice who had undergone splenectomy, or sham operation 7 days earlier. They did not find an increase in fatal staphylococcal pneumonitis under these conditions. Further laboratory definition of this complex issue is warranted.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Dec 1 1979|
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