The effect of splenectomy on pulmonary infection in newborn mice

Kerry Fagelman, H. C. Polk

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Overwhelming postsplenectomy infection is a widely discussed and studied problem. The route of infection, the specific organisms involved, and the age at splenectomy and bacterial challenge are crucial factors in determining the genuine threat of the disease. The authors studied Staphylococcus aureus respiratory infection in 10-day-old mice who had undergone splenectomy, or sham operation 7 days earlier. They did not find an increase in fatal staphylococcal pneumonitis under these conditions. Further laboratory definition of this complex issue is warranted.

Original languageEnglish (US)
Pages (from-to)766-770
Number of pages5
JournalAmerican Surgeon
Volume45
Issue number12
StatePublished - Dec 1 1979

All Science Journal Classification (ASJC) codes

  • Surgery

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