The effects of a prebiotic supplement (Prebio Support) on fecal and salivary IgA in neonatal dairy calves

V. C. Quezada-Mendoza, Arlyn Judson Heinrichs, C. M. Jones

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The newborn calf's gastrointestinal tract is sterile at birth, but by 3 days of age coliforms, Lactobacilli, and Bifidobacteria are the predominant flora in the feces. During the preweaning period, calves are susceptible to diarrhea that can lead to high levels of morbidity and mortality. Diarrhea has been related with a decrease of beneficial microbiota and an increase of coliform counts in feces. Prebiotic supplements are believed to decrease diarrhea and positively affect some parameters of the immune system. In calves, these supplements have shown some promising effects on intestinal microbial populations but there is limited information about effects on immunity. The main objectives of this study were to evaluate effects of a prebiotic supplement containing fermentation products of lactic acid bacteria on the mucosal immune system by measuring fecal and salivary IgA and to evaluate calf health and growth performance. In this trial 40 Holstein calves were randomly assigned to receive milk replacer with a prebiotic supplement (20 g/day Prebio Support; Meiji Feed Co., Ltd. Tokyo, Japan) or the same milk replacer with no prebiotic (control). Fecal and salivary IgA, calf health, plasma IgG, and lymphocyte counts were not affected by treatment. Lactobacilli count in feces was higher (P=0.05) and Bifidobacteria tended to be higher (P=0.07) in calves fed prebiotic. Prebiotic supplement increased beneficial bacteria in calves, but did not decrease overall incidence of diarrhea in this trial. Calves in this study were all affected by cryptosporidiosis and some were treated with antibiotics, so it is possible that this limited some of the effects of the prebiotic product. Fecal IgA seemed to be a good measure of mucosal immunity, and more studies are needed to develop methods to measure this type of immunity in calves.

Original languageEnglish (US)
Pages (from-to)222-228
Number of pages7
JournalLivestock Science
Volume142
Issue number1-3
DOIs
StatePublished - Dec 1 2011

Fingerprint

Prebiotics
dairy calves
prebiotics
Immunoglobulin A
calves
Diarrhea
Feces
Bifidobacterium
diarrhea
Lactobacillus
Immune System
Immunity
milk replacer
Milk
feces
Bacteria
Cryptosporidiosis
Mucosal Immunity
immune system
Tokyo

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology
  • veterinary(all)

Cite this

@article{f825b18f52f244a5bd966aaf9ee47d1e,
title = "The effects of a prebiotic supplement (Prebio Support) on fecal and salivary IgA in neonatal dairy calves",
abstract = "The newborn calf's gastrointestinal tract is sterile at birth, but by 3 days of age coliforms, Lactobacilli, and Bifidobacteria are the predominant flora in the feces. During the preweaning period, calves are susceptible to diarrhea that can lead to high levels of morbidity and mortality. Diarrhea has been related with a decrease of beneficial microbiota and an increase of coliform counts in feces. Prebiotic supplements are believed to decrease diarrhea and positively affect some parameters of the immune system. In calves, these supplements have shown some promising effects on intestinal microbial populations but there is limited information about effects on immunity. The main objectives of this study were to evaluate effects of a prebiotic supplement containing fermentation products of lactic acid bacteria on the mucosal immune system by measuring fecal and salivary IgA and to evaluate calf health and growth performance. In this trial 40 Holstein calves were randomly assigned to receive milk replacer with a prebiotic supplement (20 g/day Prebio Support™; Meiji Feed Co., Ltd. Tokyo, Japan) or the same milk replacer with no prebiotic (control). Fecal and salivary IgA, calf health, plasma IgG, and lymphocyte counts were not affected by treatment. Lactobacilli count in feces was higher (P=0.05) and Bifidobacteria tended to be higher (P=0.07) in calves fed prebiotic. Prebiotic supplement increased beneficial bacteria in calves, but did not decrease overall incidence of diarrhea in this trial. Calves in this study were all affected by cryptosporidiosis and some were treated with antibiotics, so it is possible that this limited some of the effects of the prebiotic product. Fecal IgA seemed to be a good measure of mucosal immunity, and more studies are needed to develop methods to measure this type of immunity in calves.",
author = "Quezada-Mendoza, {V. C.} and Heinrichs, {Arlyn Judson} and Jones, {C. M.}",
year = "2011",
month = "12",
day = "1",
doi = "10.1016/j.livsci.2011.07.015",
language = "English (US)",
volume = "142",
pages = "222--228",
journal = "Livestock Science",
issn = "1871-1413",
publisher = "Elsevier",
number = "1-3",

}

The effects of a prebiotic supplement (Prebio Support) on fecal and salivary IgA in neonatal dairy calves. / Quezada-Mendoza, V. C.; Heinrichs, Arlyn Judson; Jones, C. M.

In: Livestock Science, Vol. 142, No. 1-3, 01.12.2011, p. 222-228.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The effects of a prebiotic supplement (Prebio Support) on fecal and salivary IgA in neonatal dairy calves

AU - Quezada-Mendoza, V. C.

AU - Heinrichs, Arlyn Judson

AU - Jones, C. M.

PY - 2011/12/1

Y1 - 2011/12/1

N2 - The newborn calf's gastrointestinal tract is sterile at birth, but by 3 days of age coliforms, Lactobacilli, and Bifidobacteria are the predominant flora in the feces. During the preweaning period, calves are susceptible to diarrhea that can lead to high levels of morbidity and mortality. Diarrhea has been related with a decrease of beneficial microbiota and an increase of coliform counts in feces. Prebiotic supplements are believed to decrease diarrhea and positively affect some parameters of the immune system. In calves, these supplements have shown some promising effects on intestinal microbial populations but there is limited information about effects on immunity. The main objectives of this study were to evaluate effects of a prebiotic supplement containing fermentation products of lactic acid bacteria on the mucosal immune system by measuring fecal and salivary IgA and to evaluate calf health and growth performance. In this trial 40 Holstein calves were randomly assigned to receive milk replacer with a prebiotic supplement (20 g/day Prebio Support™; Meiji Feed Co., Ltd. Tokyo, Japan) or the same milk replacer with no prebiotic (control). Fecal and salivary IgA, calf health, plasma IgG, and lymphocyte counts were not affected by treatment. Lactobacilli count in feces was higher (P=0.05) and Bifidobacteria tended to be higher (P=0.07) in calves fed prebiotic. Prebiotic supplement increased beneficial bacteria in calves, but did not decrease overall incidence of diarrhea in this trial. Calves in this study were all affected by cryptosporidiosis and some were treated with antibiotics, so it is possible that this limited some of the effects of the prebiotic product. Fecal IgA seemed to be a good measure of mucosal immunity, and more studies are needed to develop methods to measure this type of immunity in calves.

AB - The newborn calf's gastrointestinal tract is sterile at birth, but by 3 days of age coliforms, Lactobacilli, and Bifidobacteria are the predominant flora in the feces. During the preweaning period, calves are susceptible to diarrhea that can lead to high levels of morbidity and mortality. Diarrhea has been related with a decrease of beneficial microbiota and an increase of coliform counts in feces. Prebiotic supplements are believed to decrease diarrhea and positively affect some parameters of the immune system. In calves, these supplements have shown some promising effects on intestinal microbial populations but there is limited information about effects on immunity. The main objectives of this study were to evaluate effects of a prebiotic supplement containing fermentation products of lactic acid bacteria on the mucosal immune system by measuring fecal and salivary IgA and to evaluate calf health and growth performance. In this trial 40 Holstein calves were randomly assigned to receive milk replacer with a prebiotic supplement (20 g/day Prebio Support™; Meiji Feed Co., Ltd. Tokyo, Japan) or the same milk replacer with no prebiotic (control). Fecal and salivary IgA, calf health, plasma IgG, and lymphocyte counts were not affected by treatment. Lactobacilli count in feces was higher (P=0.05) and Bifidobacteria tended to be higher (P=0.07) in calves fed prebiotic. Prebiotic supplement increased beneficial bacteria in calves, but did not decrease overall incidence of diarrhea in this trial. Calves in this study were all affected by cryptosporidiosis and some were treated with antibiotics, so it is possible that this limited some of the effects of the prebiotic product. Fecal IgA seemed to be a good measure of mucosal immunity, and more studies are needed to develop methods to measure this type of immunity in calves.

UR - http://www.scopus.com/inward/record.url?scp=80655124578&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80655124578&partnerID=8YFLogxK

U2 - 10.1016/j.livsci.2011.07.015

DO - 10.1016/j.livsci.2011.07.015

M3 - Article

AN - SCOPUS:80655124578

VL - 142

SP - 222

EP - 228

JO - Livestock Science

JF - Livestock Science

SN - 1871-1413

IS - 1-3

ER -