The effects of feeding fish oil on uterine secretion of PGF , milk composition, and metabolic status of periparturient Holstein cows

R. Mattos, C. R. Staples, A. Arteche, M. C. Wiltbank, Francisco Javier Diaz, T. C. Jenkins, W. W. Thatcher

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

The objectives were to determine the effect of dietary fish oil (FO) on uterine secretion of PGF, milk production, milk composition, and metabolic status during the periparturient period. Holstein cows were assigned randomly to diets containing FO (n = 13) or olive oil (OO, n = 13). Cows were fed prepartum and postpartum diets that provided approximately 200 g/d from 21 d before the expected parturition until 21 d after parturition. The FO used contained 36% eicosapentaenoic acid (EPA, C20:5, n-3) and 28% docosahexaenoic acid (DHA, C22:6, n-3). Blood samples were obtained from 14 d before the due date until d 21 postpartum. A total of 6 FO and 8 OO cows without periparturient disorders were used in the statistical analyses of PGF -metabolite (PGFM) and metabolite concentrations. Length of prepartum feeding with OO or FO did not differ. Proportions of individual and total n-3 fatty acids were increased in caruncular tissue and milk of cows fed FO. The combined concentrations of EPA and DHA in caruncular tissue were correlated positively with the number of days supplemented with FO. Cows fed FO had reduced concentrations of plasma PGFM during the 60 h immediately after parturition compared with cows fed OO. Concentrations of prostaglandin H synthase-2 mRNA and protein in caruncular tissue were unaffected by diet. Production of milk and FCM were similar between cows fed the two oil diets. However, cows fed FO produced less milk fat. Feeding FO reduced plasma concentrations of glucose. Dietary fatty acids given during the periparturient period can reduce the uterine secretion of PGF in lactating dairy cows and alter the fatty acid profile of milk fat.

Original languageEnglish (US)
Pages (from-to)921-932
Number of pages12
JournalJournal of dairy science
Volume87
Issue number4
DOIs
StatePublished - Jan 1 2004

Fingerprint

Fish Oils
Prostaglandins F
milk composition
fish oils
Milk
Holstein
secretion
cows
Diet
Dinoprost
Parturition
parturition
metabolites
diet
Postpartum Period
milk fat
milk production
Fatty Acids
dairy cows
Fats

All Science Journal Classification (ASJC) codes

  • Food Science
  • Animal Science and Zoology
  • Genetics

Cite this

Mattos, R. ; Staples, C. R. ; Arteche, A. ; Wiltbank, M. C. ; Diaz, Francisco Javier ; Jenkins, T. C. ; Thatcher, W. W. / The effects of feeding fish oil on uterine secretion of PGF , milk composition, and metabolic status of periparturient Holstein cows. In: Journal of dairy science. 2004 ; Vol. 87, No. 4. pp. 921-932.
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abstract = "The objectives were to determine the effect of dietary fish oil (FO) on uterine secretion of PGF2α, milk production, milk composition, and metabolic status during the periparturient period. Holstein cows were assigned randomly to diets containing FO (n = 13) or olive oil (OO, n = 13). Cows were fed prepartum and postpartum diets that provided approximately 200 g/d from 21 d before the expected parturition until 21 d after parturition. The FO used contained 36{\%} eicosapentaenoic acid (EPA, C20:5, n-3) and 28{\%} docosahexaenoic acid (DHA, C22:6, n-3). Blood samples were obtained from 14 d before the due date until d 21 postpartum. A total of 6 FO and 8 OO cows without periparturient disorders were used in the statistical analyses of PGF 2α-metabolite (PGFM) and metabolite concentrations. Length of prepartum feeding with OO or FO did not differ. Proportions of individual and total n-3 fatty acids were increased in caruncular tissue and milk of cows fed FO. The combined concentrations of EPA and DHA in caruncular tissue were correlated positively with the number of days supplemented with FO. Cows fed FO had reduced concentrations of plasma PGFM during the 60 h immediately after parturition compared with cows fed OO. Concentrations of prostaglandin H synthase-2 mRNA and protein in caruncular tissue were unaffected by diet. Production of milk and FCM were similar between cows fed the two oil diets. However, cows fed FO produced less milk fat. Feeding FO reduced plasma concentrations of glucose. Dietary fatty acids given during the periparturient period can reduce the uterine secretion of PGF2α in lactating dairy cows and alter the fatty acid profile of milk fat.",
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The effects of feeding fish oil on uterine secretion of PGF , milk composition, and metabolic status of periparturient Holstein cows. / Mattos, R.; Staples, C. R.; Arteche, A.; Wiltbank, M. C.; Diaz, Francisco Javier; Jenkins, T. C.; Thatcher, W. W.

In: Journal of dairy science, Vol. 87, No. 4, 01.01.2004, p. 921-932.

Research output: Contribution to journalArticle

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T1 - The effects of feeding fish oil on uterine secretion of PGF 2α, milk composition, and metabolic status of periparturient Holstein cows

AU - Mattos, R.

AU - Staples, C. R.

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AB - The objectives were to determine the effect of dietary fish oil (FO) on uterine secretion of PGF2α, milk production, milk composition, and metabolic status during the periparturient period. Holstein cows were assigned randomly to diets containing FO (n = 13) or olive oil (OO, n = 13). Cows were fed prepartum and postpartum diets that provided approximately 200 g/d from 21 d before the expected parturition until 21 d after parturition. The FO used contained 36% eicosapentaenoic acid (EPA, C20:5, n-3) and 28% docosahexaenoic acid (DHA, C22:6, n-3). Blood samples were obtained from 14 d before the due date until d 21 postpartum. A total of 6 FO and 8 OO cows without periparturient disorders were used in the statistical analyses of PGF 2α-metabolite (PGFM) and metabolite concentrations. Length of prepartum feeding with OO or FO did not differ. Proportions of individual and total n-3 fatty acids were increased in caruncular tissue and milk of cows fed FO. The combined concentrations of EPA and DHA in caruncular tissue were correlated positively with the number of days supplemented with FO. Cows fed FO had reduced concentrations of plasma PGFM during the 60 h immediately after parturition compared with cows fed OO. Concentrations of prostaglandin H synthase-2 mRNA and protein in caruncular tissue were unaffected by diet. Production of milk and FCM were similar between cows fed the two oil diets. However, cows fed FO produced less milk fat. Feeding FO reduced plasma concentrations of glucose. Dietary fatty acids given during the periparturient period can reduce the uterine secretion of PGF2α in lactating dairy cows and alter the fatty acid profile of milk fat.

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