The evolution of courtship behaviors through the origination of a new gene in Drosophila

Hongzheng Dai, Ying Chen, Sidi Chen, Qiyan Mao, David Kennedy, Patrick Landback, Adam Eyre-Walker, Wei Du, Manyuan Long

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

New genes can originate by the combination of sequences from unrelated genes or their duplicates to form a chimeric structure. These chimeric genes often evolve rapidly, suggesting that they undergo adaptive evolution and may therefore be involved in novel phenotypes. Their functions, however, are rarely known. Here, we describe the phenotypic effects of a chimeric gene, sphinx, that has recently evolved in Drosophila melanogaster. We show that a knockout of this gene leads to increased male-male courtship in D. melanogaster, although it leaves other aspects of mating behavior unchanged. Comparative studies of courtship behavior in other closely related Drosophila species suggest that this mutant phenotype of male-male courtship is the ancestral condition because these related species show much higher levels of male-male courtship than D. melanogaster. D. melanogaster therefore seems to have evolved in its courtship behaviors by the recruitment of a new chimeric gene.

Original languageEnglish (US)
Pages (from-to)7478-7483
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume105
Issue number21
DOIs
StatePublished - May 27 2008

All Science Journal Classification (ASJC) codes

  • General

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