The evolution of virulence

Research output: Contribution to journalReview article

230 Scopus citations

Abstract

Why is there variation in the virulence of infectious diseases? Virulence can have substantial effects on the genetic contribution of both host and pathogen to future generations. Understanding it therefore requires explanation not only in terms of cellular and molecular mechanisms1, 2, but also in evolutionary terms: what is the nature of the selection acting on genes responsible for virulence?

Original languageEnglish (US)
Pages (from-to)73-76
Number of pages4
JournalTrends in Microbiology
Volume2
Issue number3
DOIs
StatePublished - Mar 1994

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

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