The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update

Enis Afgan, Dannon Baker, Marius van den Beek, Daniel Blankenberg, Dave Bouvier, Martin Čech, John Chilton, Dave Clements, Nate Coraor, Carl Eberhard, Björn Grüning, Aysam Guerler, Jennifer Hillman-Jackson, Greg Von Kuster, Eric Rasche, Nicola Soranzo, Nitesh Turaga, James Taylor, Anton Nekrutenko, Jeremy Goecks

Research output: Contribution to journalArticle

706 Citations (Scopus)

Abstract

High-throughput data production technologies, particularly 'next-generation' DNA sequencing, have ushered in widespread and disruptive changes to biomedical research. Making sense of the large datasets produced by these technologies requires sophisticated statistical and computational methods, as well as substantial computational power. This has led to an acute crisis in life sciences, as researchers without informatics training attempt to perform computation-dependent analyses. Since 2005, the Galaxy project has worked to address this problem by providing a framework that makes advanced computational tools usable by non experts. Galaxy seeks to make data-intensive research more accessible, transparent and reproducible by providing a Web-based environment in which users can perform computational analyses and have all of the details automatically tracked for later inspection, publication, or reuse. In this report we highlight recently added features enabling biomedical analyses on a large scale.

Original languageEnglish (US)
Pages (from-to)W3-W10
JournalNucleic acids research
Volume44
Issue numberW1
DOIs
StatePublished - Jul 8 2016

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Galaxies
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Informatics
Biological Science Disciplines
DNA Sequence Analysis
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Biomedical Research
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All Science Journal Classification (ASJC) codes

  • Genetics

Cite this

Afgan, E., Baker, D., van den Beek, M., Blankenberg, D., Bouvier, D., Čech, M., ... Goecks, J. (2016). The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic acids research, 44(W1), W3-W10. https://doi.org/10.1093/nar/gkw343
Afgan, Enis ; Baker, Dannon ; van den Beek, Marius ; Blankenberg, Daniel ; Bouvier, Dave ; Čech, Martin ; Chilton, John ; Clements, Dave ; Coraor, Nate ; Eberhard, Carl ; Grüning, Björn ; Guerler, Aysam ; Hillman-Jackson, Jennifer ; Von Kuster, Greg ; Rasche, Eric ; Soranzo, Nicola ; Turaga, Nitesh ; Taylor, James ; Nekrutenko, Anton ; Goecks, Jeremy. / The Galaxy platform for accessible, reproducible and collaborative biomedical analyses : 2016 update. In: Nucleic acids research. 2016 ; Vol. 44, No. W1. pp. W3-W10.
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Afgan, E, Baker, D, van den Beek, M, Blankenberg, D, Bouvier, D, Čech, M, Chilton, J, Clements, D, Coraor, N, Eberhard, C, Grüning, B, Guerler, A, Hillman-Jackson, J, Von Kuster, G, Rasche, E, Soranzo, N, Turaga, N, Taylor, J, Nekrutenko, A & Goecks, J 2016, 'The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update', Nucleic acids research, vol. 44, no. W1, pp. W3-W10. https://doi.org/10.1093/nar/gkw343

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses : 2016 update. / Afgan, Enis; Baker, Dannon; van den Beek, Marius; Blankenberg, Daniel; Bouvier, Dave; Čech, Martin; Chilton, John; Clements, Dave; Coraor, Nate; Eberhard, Carl; Grüning, Björn; Guerler, Aysam; Hillman-Jackson, Jennifer; Von Kuster, Greg; Rasche, Eric; Soranzo, Nicola; Turaga, Nitesh; Taylor, James; Nekrutenko, Anton; Goecks, Jeremy.

In: Nucleic acids research, Vol. 44, No. W1, 08.07.2016, p. W3-W10.

Research output: Contribution to journalArticle

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AU - Čech, Martin

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AU - Clements, Dave

AU - Coraor, Nate

AU - Eberhard, Carl

AU - Grüning, Björn

AU - Guerler, Aysam

AU - Hillman-Jackson, Jennifer

AU - Von Kuster, Greg

AU - Rasche, Eric

AU - Soranzo, Nicola

AU - Turaga, Nitesh

AU - Taylor, James

AU - Nekrutenko, Anton

AU - Goecks, Jeremy

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