The genetic analysis of repeated measures. I. Simplex models

Dorret I. Boomsma; Peter C.M. Molenaar

doi:10.1007/BF01065991

The genetic analysis of repeated measures. I. Simplex models

Dorret I. Boomsma, Peter C.M. Molenaar

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Abstract

The well-known simplex model is extended to a model that may be used for the genetic and environmental analysis of covariance structures. This "double" simplex structure can be specified as a LISREL model. It is shown that data which give rise to a simplex correlation structure, such as repeated-measures data, do not fit a factor-analysis model. The parameter estimation of the simplex model is illustrated with computer-simulated twin data.

Original language	English (US)
Pages (from-to)	111-123
Number of pages	13
Journal	Behavior Genetics
Volume	17
Issue number	2
DOIs	https://doi.org/10.1007/BF01065991
State	Published - Mar 1987

All Science Journal Classification (ASJC) codes

Ecology, Evolution, Behavior and Systematics
Genetics
Genetics(clinical)

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10.1007/BF01065991

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AB - The well-known simplex model is extended to a model that may be used for the genetic and environmental analysis of covariance structures. This "double" simplex structure can be specified as a LISREL model. It is shown that data which give rise to a simplex correlation structure, such as repeated-measures data, do not fit a factor-analysis model. The parameter estimation of the simplex model is illustrated with computer-simulated twin data.

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The genetic analysis of repeated measures. I. Simplex models

Abstract

All Science Journal Classification (ASJC) codes

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