The genetic demography of the Gainj of Papua New Guinea. I. Local differentiation of blood group, red cell enzyme, and serum protein allele frequencies

James William Wood, P. L. Johnson, R. L. Kirk, K. McLoughlin, N. M. Blake, F. A. Matheson

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Allele frequencies are reported for 19 blood group, red cell enzyme, and serum protein loci (ABO, Rh, MN, Hb‐A, LDH‐A, LDH‐B, SOD, PGM‐1, PGM‐2, 6PGD, GPT, ESD, ADA, ACP, PGK, MDH, Alb, Hp, and Tf) determined from 310 blood samples collected among the Gainj, a small population of tribal horticulturalists from highland Papua New Guinea. Fourteen of these loci display genetic variants, and ten of them are sufficiently polymorphic to permit a preliminary analysis of Gainj population structure. Patterns of variation among subdivisions of the population are analyzed using an approach analogous to a multivariate analysis of variance with unbalanced design, and weighted genetic distances are extracted from the results. The distance analysis indicates that patterns of genetic variation within this population reflect the geographical distribution of subdivisions, as well as subdivision size and movement among subdivisions. A parallel analysis of the Gainj and two other tribal groups from highland New Guinea, the Murapin Enga and the Simbai Valley Maring, suggests that the Gainj are both genetically divergent from neighboring populations and internally highly differentiated.

Original languageEnglish (US)
Pages (from-to)15-25
Number of pages11
JournalAmerican Journal of Physical Anthropology
Volume57
Issue number1
DOIs
StatePublished - Jan 1 1982

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Papua New Guinea
Papua-New Guinea
demography
Blood Group Antigens
Gene Frequency
Blood Proteins
Demography
Enzymes
Population
New Guinea
Genetic Loci
analysis of variance
multivariate analysis
Analysis of Variance
Multivariate Analysis
Group

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Anthropology

Cite this

Wood, James William ; Johnson, P. L. ; Kirk, R. L. ; McLoughlin, K. ; Blake, N. M. ; Matheson, F. A. / The genetic demography of the Gainj of Papua New Guinea. I. Local differentiation of blood group, red cell enzyme, and serum protein allele frequencies. In: American Journal of Physical Anthropology. 1982 ; Vol. 57, No. 1. pp. 15-25.
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The genetic demography of the Gainj of Papua New Guinea. I. Local differentiation of blood group, red cell enzyme, and serum protein allele frequencies. / Wood, James William; Johnson, P. L.; Kirk, R. L.; McLoughlin, K.; Blake, N. M.; Matheson, F. A.

In: American Journal of Physical Anthropology, Vol. 57, No. 1, 01.01.1982, p. 15-25.

Research output: Contribution to journalArticle

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