The genetic legacy of paleolithic Homo sapiens sapiens in extant europeans: A Y chromosome perspective

O. Semino, G. Passarino, P. J. Oefner, A. A. Lin, S. Arbuzova, L. E. Beckman, G. De Benedictis, P. Francalacci, A. Kouvatsi, S. Limborska, M. Marcikiae, A. Mika, B. Mika, Dragan Primorac, A. S. Santachiara-Benerecetti, L. L. Cavalli-Sforza, P. A. Underhill

Research output: Contribution to journalArticle

606 Scopus citations

Abstract

A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution and age estimates of alleles are compatible with two Paleolithic and one Neolithic migratory episode that have contributed to the modern European gene pool. A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.

Original languageEnglish (US)
Pages (from-to)1155-1159
Number of pages5
JournalScience
Volume290
Issue number5494
DOIs
StatePublished - Nov 10 2000

All Science Journal Classification (ASJC) codes

  • General

Fingerprint Dive into the research topics of 'The genetic legacy of paleolithic Homo sapiens sapiens in extant europeans: A Y chromosome perspective'. Together they form a unique fingerprint.

  • Cite this

    Semino, O., Passarino, G., Oefner, P. J., Lin, A. A., Arbuzova, S., Beckman, L. E., De Benedictis, G., Francalacci, P., Kouvatsi, A., Limborska, S., Marcikiae, M., Mika, A., Mika, B., Primorac, D., Santachiara-Benerecetti, A. S., Cavalli-Sforza, L. L., & Underhill, P. A. (2000). The genetic legacy of paleolithic Homo sapiens sapiens in extant europeans: A Y chromosome perspective. Science, 290(5494), 1155-1159. https://doi.org/10.1126/science.290.5494.1155