The genome of the diatom Thalassiosira Pseudonana: Ecology, evolution, and metabolism

E. Virginia Armbrust, John A. Berges, Chris Bowler, Beverley R. Green, Diego Martinez, Nicholas H. Putnam, Shiguo Zhou, Andrew E. Allen, Kirk E. Apt, Michael Bechner, Mark A. Brzezinski, Balbir K. Chaal, Anthony Chiovitti, Aubrey K. Davis, Mark S. Demarest, J. Chris Detter, Tijana Glavina, David Goodstein, Masood Z. Hadi, Uffe HellstenMark Hildebrand, Bethany D. Jenkins, Jerzy Jurka, Vladimir V. Kapitonov, Nils Kröger, Winnie W.Y. Lau, Todd W. Lane, Frank W. Larimer, J. Casey Lippmeier, Susan Lucas, Mónica Medina, Anton Montsant, Miroslav Obornik, Micaela Schnitzler Parker, Brian Palenik, Gregory J. Pazour, Paul M. Richardson, Tatiana A. Rynearson, Mak A. Saito, David C. Schwartz, Kimberlee Thamatrakoln, Klaus Valentin, Assaf Vardi, Frances P. Wilkerson, Daniel S. Rokhsar

Research output: Contribution to journalArticle

1312 Scopus citations

Abstract

Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are responsible for ∼20% of global carbon fixation. We report the 34 million - base pair draft nuclear genome of the marine diatom Thalassiosira pseudonana and its 129 thousand - base pair plastid and 44 thousand - base pair mitochondrial genomes. Sequence and optical restriction mapping revealed 24 diploid nuclear chromosomes. We identified novel genes for silicic acid transport and formation of silica-based cell walls, high-affinity iron uptake, biosynthetic enzymes for several types of polyunsaturated fatty acids, use of a range of nitrogenous compounds, and a complete urea cycle, all attributes that allow diatoms to prosper in aquatic environments.

Original languageEnglish (US)
Pages (from-to)79-86
Number of pages8
JournalScience
Volume306
Issue number5693
DOIs
StatePublished - Oct 1 2004

All Science Journal Classification (ASJC) codes

  • General

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    Armbrust, E. V., Berges, J. A., Bowler, C., Green, B. R., Martinez, D., Putnam, N. H., Zhou, S., Allen, A. E., Apt, K. E., Bechner, M., Brzezinski, M. A., Chaal, B. K., Chiovitti, A., Davis, A. K., Demarest, M. S., Detter, J. C., Glavina, T., Goodstein, D., Hadi, M. Z., ... Rokhsar, D. S. (2004). The genome of the diatom Thalassiosira Pseudonana: Ecology, evolution, and metabolism. Science, 306(5693), 79-86. https://doi.org/10.1126/science.1101156