The Hopkins Lupus Pregnancy Center

1987-1991 Update

M. Petri, D. Howard, John Repke, D. W. Goldman

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

The course of pregnancy in patients with systemic lupus erythematosus is not known. The Hopkins Lupus Pregnancy Center has followed 64 patients (74 pregnancies) prospectively since 1987. Patients are seen monthly and clinical and pregnancy-related data collected, with particular emphasis on the occurrence of lupus flare. Flare rate during pregnancy was 1.63 per person- year, compared to 0.64-0.65 after delivery or in non-pregnant patients. Flare did not influence pregnancy outcome. Low serum C3 or C4 and high anticardiolipin antibody predicted pregnancy loss, and prednisone dose, aspirin use, diastolic second trimester blood pressure, C3 at first visit, and race predicted preterm birth. Maternal flare and preterm birth are important risks in lupus pregnancy. The latter can be predicted from maternal pregnancy data.

Original languageEnglish (US)
Pages (from-to)188-191
Number of pages4
JournalAmerican Journal of Reproductive Immunology
Volume28
Issue number3-4
StatePublished - Dec 1 1992

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Pregnancy
Premature Birth
Mothers
Anticardiolipin Antibodies
Second Pregnancy Trimester
Pregnancy Rate
Pregnancy Outcome
Prednisone
Systemic Lupus Erythematosus
Aspirin
Blood Pressure
Serum

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

Petri, M. ; Howard, D. ; Repke, John ; Goldman, D. W. / The Hopkins Lupus Pregnancy Center : 1987-1991 Update. In: American Journal of Reproductive Immunology. 1992 ; Vol. 28, No. 3-4. pp. 188-191.
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Petri, M, Howard, D, Repke, J & Goldman, DW 1992, 'The Hopkins Lupus Pregnancy Center: 1987-1991 Update', American Journal of Reproductive Immunology, vol. 28, no. 3-4, pp. 188-191.

The Hopkins Lupus Pregnancy Center : 1987-1991 Update. / Petri, M.; Howard, D.; Repke, John; Goldman, D. W.

In: American Journal of Reproductive Immunology, Vol. 28, No. 3-4, 01.12.1992, p. 188-191.

Research output: Contribution to journalArticle

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