The importance of rhinitis on sleep, daytime somnolence, productivity and fatigue

Lesley Woods, Timothy J. Craig

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

PURPOSE OF REVIEW: The goal of treatment of allergic rhinitis should include improvement of daytime and nighttime symptoms, sleep, and quality of life. Congestion from allergic rhinitis is associated with decreased learning and productivity at work and school and a reduced quality of life. The release of inflammatory mediators and activation of inflammatory cells results in nasal congestion, causing disrupted sleep and subsequent daytime somnolence. RECENT FINDINGS: This review presents evidence that allergic rhinitis causes sleep disruption, and discusses the pathophysiology of this process. The medications used to treat allergic rhinitis and their ability to improve sleep in patients with allergic rhinitis are reviewed. SUMMARY: Some allergic rhinitis medications can be sedating; therefore, it is important to treat allergic rhinitis with medications that improve symptoms while producing few adverse effects. Medications such as the second-generation antihistamines and anticholinergic drugs are well tolerated, but have little effect on congestion. Intranasal corticosteroids reduce congestion, improve sleep and sleep problems, and reduce daytime sleepiness, fatigue, and inflammation. Recently, montelukast, a leukotriene receptor antagonist, has been added to the therapies approved for allergic rhinitis. Montelukast significantly improves both daytime and nighttime symptoms.

Original languageEnglish (US)
Pages (from-to)390-396
Number of pages7
JournalCurrent opinion in pulmonary medicine
Volume12
Issue number6
DOIs
StatePublished - Nov 1 2006

Fingerprint

Rhinitis
Fatigue
Sleep
Efficiency
montelukast
Non-Sedating Histamine H1 Antagonists
Quality of Life
Leukotriene Antagonists
Aptitude
Allergic Rhinitis
Cholinergic Antagonists
Nose
Adrenal Cortex Hormones
Learning
Inflammation
Therapeutics
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

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abstract = "PURPOSE OF REVIEW: The goal of treatment of allergic rhinitis should include improvement of daytime and nighttime symptoms, sleep, and quality of life. Congestion from allergic rhinitis is associated with decreased learning and productivity at work and school and a reduced quality of life. The release of inflammatory mediators and activation of inflammatory cells results in nasal congestion, causing disrupted sleep and subsequent daytime somnolence. RECENT FINDINGS: This review presents evidence that allergic rhinitis causes sleep disruption, and discusses the pathophysiology of this process. The medications used to treat allergic rhinitis and their ability to improve sleep in patients with allergic rhinitis are reviewed. SUMMARY: Some allergic rhinitis medications can be sedating; therefore, it is important to treat allergic rhinitis with medications that improve symptoms while producing few adverse effects. Medications such as the second-generation antihistamines and anticholinergic drugs are well tolerated, but have little effect on congestion. Intranasal corticosteroids reduce congestion, improve sleep and sleep problems, and reduce daytime sleepiness, fatigue, and inflammation. Recently, montelukast, a leukotriene receptor antagonist, has been added to the therapies approved for allergic rhinitis. Montelukast significantly improves both daytime and nighttime symptoms.",
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The importance of rhinitis on sleep, daytime somnolence, productivity and fatigue. / Woods, Lesley; Craig, Timothy J.

In: Current opinion in pulmonary medicine, Vol. 12, No. 6, 01.11.2006, p. 390-396.

Research output: Contribution to journalReview article

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