The insomnia with short sleep duration phenotype: An update on it's importance for health and prevention

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

Purpose of review It was first proposed in the late 1990s that objective markers of sleep disturbance could serve as an index of the biological severity of insomnia. In 2013, a heuristic model of two insomnia phenotypes based on objective sleep duration was proposed. Herein, we review the studies conducted in the past 3 years on the insomnia with short sleep duration phenotype and its implications for a clinical research agenda. Recent findings Studies have shown that insomnia with objective short sleep duration is associated with physiologic hyperarousal and cardiometabolic and neurocognitive morbidity, whereas insomnia with normal sleep duration is not. Both insomnia phenotypes are associated with psychiatric morbidity albeit through different psychobiological mechanisms. Novel recent studies have included occupational outcomes, developmental approaches, at-home objective sleep testing, diagnostic accuracy measures, and response to cognitivebehavioral treatment. Summary Accumulating evidence in the past years has continued to support that insomnia with short sleep duration is a more severe phenotype of the disorder associated with physiologic changes, significant morbidity and mortality and, potentially, a differential response to treatment.

Original languageEnglish (US)
Pages (from-to)56-63
Number of pages8
JournalCurrent Opinion in Psychiatry
Volume30
Issue number1
DOIs
StatePublished - Jan 1 2017

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Sleep Initiation and Maintenance Disorders
Sleep
Health
Morbidity
Phenotype
Sleep Wake Disorders
Psychiatry
Mortality
Therapeutics
Research

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

Cite this

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The insomnia with short sleep duration phenotype : An update on it's importance for health and prevention. / Fernandez-Mendoza, Julio.

In: Current Opinion in Psychiatry, Vol. 30, No. 1, 01.01.2017, p. 56-63.

Research output: Contribution to journalReview article

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