The Intranodal Presence of Coexisting Granulomatous Inflammation and Carcinoma during Transbronchial Needle Aspiration of Intrathoracic Lymphadenopathy

Christopher R. Gilbert, Catherine Abendroth, Lonny B. Yarmus

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The presence of intrathoracic lymphadenopathy in patients with suspected malignancy remains concerning, often prompting further evaluation with tissue sampling. The presence of nodal granulomatous inflammation in patients with underlying malignancy is well reported. However, review of 3 recent large trials of endobronchial ultrasound-guided transbronchial needle aspiration in patients with granulomatous inflammation and malignancy did not identify the presence of coexisting, intranodal malignancy, and granulomatous inflammation, rather these diagnoses remained nodally exclusive. We present a case of coexisting granulomatous inflammation and metastatic carcinoma within the same lymph node aspirates, reviewing the potential diagnostic pitfalls and implications of this rare occurrence.

Original languageEnglish (US)
Pages (from-to)80-83
Number of pages4
JournalJournal of Bronchology and Interventional Pulmonology
Volume24
Issue number1
DOIs
StatePublished - Feb 1 2017

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

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