The major histocompatibility complex of the mouse

Jan Klein

Research output: Contribution to journalArticle

248 Citations (Scopus)

Abstract

Like physicists striving to develop a unified field theory, immunologists are attempting to bring order to the microcosmos of defense reactions. Indications are that one of the most important constants in this microcosmos is the major histocompatibility complex (MHC) of the species. A test of any interpretation of the MHC's role in immunity is how well it explains this system's polymorphism. One of the most crucial questions an MHC hypothesis must answer is: Why are there so many alleles at this complex?

Original languageEnglish (US)
Pages (from-to)516-521
Number of pages6
JournalScience
Volume203
Issue number4380
DOIs
StatePublished - Jan 1 1979

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Major Histocompatibility Complex
Immunity
Alleles

All Science Journal Classification (ASJC) codes

  • General

Cite this

Klein, Jan. / The major histocompatibility complex of the mouse. In: Science. 1979 ; Vol. 203, No. 4380. pp. 516-521.
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The major histocompatibility complex of the mouse. / Klein, Jan.

In: Science, Vol. 203, No. 4380, 01.01.1979, p. 516-521.

Research output: Contribution to journalArticle

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