The Prevalence of Anosmia and Associated Factors among U.S. Black and White Older Adults

Jing Dong, Jayant M. Pinto, Xuguang Guo, Alvaro Alonso, Gregory Tranah, Jane A. Cauley, Melissa Garcia, Suzanne Satterfield, Xuemei Huang, Tamara Harris, Thomas H. Mosley, Honglei Chen

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: Olfactory impairment is common among older adults; however, data are largely limited to whites. Methods: We conducted pooled analyses of two community-based studies: the Atherosclerosis Risk in Communities study (ARIC, 1,398 blacks and 4,665 whites), and the Health, Aging, and Body Composition study (Health ABC, 958 blacks and 1,536 whites) to determine the prevalence of anosmia and associated factors for black and white older adults in the United States. Results: The overall prevalence of anosmia was 22.3% among blacks and 10.4% among whites. Blacks had a markedly higher odds of anosmia compared to whites in age and sex adjusted analyses (odds ratio [OR] 2.96, 95% confidence interval [CI] = 2.59-3.38). In both blacks and whites, higher anosmia prevalence was associated with older age and male sex. The highest prevalence was found in black men 85 years or older (58.3%), and the lowest in white women aged 65-69 years (2.4%). Higher education level, lower cognitive score, ApoE 4, daytime sleepiness, poorer general health status, lower body mass index, and Parkinson disease were associated with higher prevalence of anosmia in one or both races. However, the racial difference in anosmia remained statistically significant after adjusting for these factors (fully adjusted OR = 1.76, 95%CI: 1.50-2.07). Results were comparable between the two cohorts. Discussion: Anosmia is common in older adults, particularly among blacks. Further studies are needed to identify risk factors for anosmia and to investigate racial disparities in this sensory deficit.

Original languageEnglish (US)
Pages (from-to)1080-1086
Number of pages7
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume72
Issue number8
DOIs
StatePublished - Aug 1 2017

Fingerprint

Olfaction Disorders
Odds Ratio
Confidence Intervals
hydroquinone
Health
Apolipoproteins E
Body Composition
Health Status
Parkinson Disease
Atherosclerosis
Body Mass Index
Education

All Science Journal Classification (ASJC) codes

  • Aging
  • Geriatrics and Gerontology

Cite this

Dong, Jing ; Pinto, Jayant M. ; Guo, Xuguang ; Alonso, Alvaro ; Tranah, Gregory ; Cauley, Jane A. ; Garcia, Melissa ; Satterfield, Suzanne ; Huang, Xuemei ; Harris, Tamara ; Mosley, Thomas H. ; Chen, Honglei. / The Prevalence of Anosmia and Associated Factors among U.S. Black and White Older Adults. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2017 ; Vol. 72, No. 8. pp. 1080-1086.
@article{f8f6742424004a6b848b6d95ecaff4f4,
title = "The Prevalence of Anosmia and Associated Factors among U.S. Black and White Older Adults",
abstract = "Background: Olfactory impairment is common among older adults; however, data are largely limited to whites. Methods: We conducted pooled analyses of two community-based studies: the Atherosclerosis Risk in Communities study (ARIC, 1,398 blacks and 4,665 whites), and the Health, Aging, and Body Composition study (Health ABC, 958 blacks and 1,536 whites) to determine the prevalence of anosmia and associated factors for black and white older adults in the United States. Results: The overall prevalence of anosmia was 22.3{\%} among blacks and 10.4{\%} among whites. Blacks had a markedly higher odds of anosmia compared to whites in age and sex adjusted analyses (odds ratio [OR] 2.96, 95{\%} confidence interval [CI] = 2.59-3.38). In both blacks and whites, higher anosmia prevalence was associated with older age and male sex. The highest prevalence was found in black men 85 years or older (58.3{\%}), and the lowest in white women aged 65-69 years (2.4{\%}). Higher education level, lower cognitive score, ApoE 4, daytime sleepiness, poorer general health status, lower body mass index, and Parkinson disease were associated with higher prevalence of anosmia in one or both races. However, the racial difference in anosmia remained statistically significant after adjusting for these factors (fully adjusted OR = 1.76, 95{\%}CI: 1.50-2.07). Results were comparable between the two cohorts. Discussion: Anosmia is common in older adults, particularly among blacks. Further studies are needed to identify risk factors for anosmia and to investigate racial disparities in this sensory deficit.",
author = "Jing Dong and Pinto, {Jayant M.} and Xuguang Guo and Alvaro Alonso and Gregory Tranah and Cauley, {Jane A.} and Melissa Garcia and Suzanne Satterfield and Xuemei Huang and Tamara Harris and Mosley, {Thomas H.} and Honglei Chen",
year = "2017",
month = "8",
day = "1",
doi = "10.1093/gerona/glx081",
language = "English (US)",
volume = "72",
pages = "1080--1086",
journal = "Journals of Gerontology - Series A Biological Sciences and Medical Sciences",
issn = "1079-5006",
publisher = "Oxford University Press",
number = "8",

}

Dong, J, Pinto, JM, Guo, X, Alonso, A, Tranah, G, Cauley, JA, Garcia, M, Satterfield, S, Huang, X, Harris, T, Mosley, TH & Chen, H 2017, 'The Prevalence of Anosmia and Associated Factors among U.S. Black and White Older Adults', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 72, no. 8, pp. 1080-1086. https://doi.org/10.1093/gerona/glx081

The Prevalence of Anosmia and Associated Factors among U.S. Black and White Older Adults. / Dong, Jing; Pinto, Jayant M.; Guo, Xuguang; Alonso, Alvaro; Tranah, Gregory; Cauley, Jane A.; Garcia, Melissa; Satterfield, Suzanne; Huang, Xuemei; Harris, Tamara; Mosley, Thomas H.; Chen, Honglei.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 72, No. 8, 01.08.2017, p. 1080-1086.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The Prevalence of Anosmia and Associated Factors among U.S. Black and White Older Adults

AU - Dong, Jing

AU - Pinto, Jayant M.

AU - Guo, Xuguang

AU - Alonso, Alvaro

AU - Tranah, Gregory

AU - Cauley, Jane A.

AU - Garcia, Melissa

AU - Satterfield, Suzanne

AU - Huang, Xuemei

AU - Harris, Tamara

AU - Mosley, Thomas H.

AU - Chen, Honglei

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Background: Olfactory impairment is common among older adults; however, data are largely limited to whites. Methods: We conducted pooled analyses of two community-based studies: the Atherosclerosis Risk in Communities study (ARIC, 1,398 blacks and 4,665 whites), and the Health, Aging, and Body Composition study (Health ABC, 958 blacks and 1,536 whites) to determine the prevalence of anosmia and associated factors for black and white older adults in the United States. Results: The overall prevalence of anosmia was 22.3% among blacks and 10.4% among whites. Blacks had a markedly higher odds of anosmia compared to whites in age and sex adjusted analyses (odds ratio [OR] 2.96, 95% confidence interval [CI] = 2.59-3.38). In both blacks and whites, higher anosmia prevalence was associated with older age and male sex. The highest prevalence was found in black men 85 years or older (58.3%), and the lowest in white women aged 65-69 years (2.4%). Higher education level, lower cognitive score, ApoE 4, daytime sleepiness, poorer general health status, lower body mass index, and Parkinson disease were associated with higher prevalence of anosmia in one or both races. However, the racial difference in anosmia remained statistically significant after adjusting for these factors (fully adjusted OR = 1.76, 95%CI: 1.50-2.07). Results were comparable between the two cohorts. Discussion: Anosmia is common in older adults, particularly among blacks. Further studies are needed to identify risk factors for anosmia and to investigate racial disparities in this sensory deficit.

AB - Background: Olfactory impairment is common among older adults; however, data are largely limited to whites. Methods: We conducted pooled analyses of two community-based studies: the Atherosclerosis Risk in Communities study (ARIC, 1,398 blacks and 4,665 whites), and the Health, Aging, and Body Composition study (Health ABC, 958 blacks and 1,536 whites) to determine the prevalence of anosmia and associated factors for black and white older adults in the United States. Results: The overall prevalence of anosmia was 22.3% among blacks and 10.4% among whites. Blacks had a markedly higher odds of anosmia compared to whites in age and sex adjusted analyses (odds ratio [OR] 2.96, 95% confidence interval [CI] = 2.59-3.38). In both blacks and whites, higher anosmia prevalence was associated with older age and male sex. The highest prevalence was found in black men 85 years or older (58.3%), and the lowest in white women aged 65-69 years (2.4%). Higher education level, lower cognitive score, ApoE 4, daytime sleepiness, poorer general health status, lower body mass index, and Parkinson disease were associated with higher prevalence of anosmia in one or both races. However, the racial difference in anosmia remained statistically significant after adjusting for these factors (fully adjusted OR = 1.76, 95%CI: 1.50-2.07). Results were comparable between the two cohorts. Discussion: Anosmia is common in older adults, particularly among blacks. Further studies are needed to identify risk factors for anosmia and to investigate racial disparities in this sensory deficit.

UR - http://www.scopus.com/inward/record.url?scp=85026870667&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026870667&partnerID=8YFLogxK

U2 - 10.1093/gerona/glx081

DO - 10.1093/gerona/glx081

M3 - Article

C2 - 28498937

AN - SCOPUS:85026870667

VL - 72

SP - 1080

EP - 1086

JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences

JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences

SN - 1079-5006

IS - 8

ER -