The Relation of Passive Smoking to Lung Cancer

Annette Stemhagen, Linda Williams Pickle, Elizabeth Fontham

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

To evaluate the role of passive smoking in the development of lung cancer among nonsmokers, data were pooled from three large incident case-control interview studies. Ninety-nine lung cancer cases and 736 controls never used any form of tobacco. Overall the adjusted odds ratio for lung cancer among nonsmokers ever living with a smoker was 0.8 (95% confidence interval, 0.5-1.3) rising to 1.2 among those exposed for 40 or more years. Persons living with a spouse who smoked cigarettes were at increased risk (adjusted odds ratio, 1.5; 95% confidence interval, 0.8-2.8). When adjusted for age and gender, there was a significant trend in risk with increasing amounts smoked per week by the spouse (P = 0.05) and with cumulative pack-years of exposure (P = 0.03). This effect was limited to females, especially older women whose husbands were heavy smokers. The elevated risk associated with spouse smoking was restricted to squamous and small cell carcinomas (odds ratio, 2.9; 95% confidence interval, 0.9-93), which provides additional evidence linking passive smoking to lung cancer.

Original languageEnglish (US)
Pages (from-to)4808-4811
Number of pages4
JournalCancer Research
Volume46
Issue number9
StatePublished - Jan 1 1986

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Tobacco Smoke Pollution
Spouses
Lung Neoplasms
Odds Ratio
Confidence Intervals
Small Cell Carcinoma
Tobacco Products
Tobacco
Case-Control Studies
Squamous Cell Carcinoma
Smoking
Interviews

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Stemhagen, A., Pickle, L. W., & Fontham, E. (1986). The Relation of Passive Smoking to Lung Cancer. Cancer Research, 46(9), 4808-4811.
Stemhagen, Annette ; Pickle, Linda Williams ; Fontham, Elizabeth. / The Relation of Passive Smoking to Lung Cancer. In: Cancer Research. 1986 ; Vol. 46, No. 9. pp. 4808-4811.
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Stemhagen, A, Pickle, LW & Fontham, E 1986, 'The Relation of Passive Smoking to Lung Cancer', Cancer Research, vol. 46, no. 9, pp. 4808-4811.

The Relation of Passive Smoking to Lung Cancer. / Stemhagen, Annette; Pickle, Linda Williams; Fontham, Elizabeth.

In: Cancer Research, Vol. 46, No. 9, 01.01.1986, p. 4808-4811.

Research output: Contribution to journalArticle

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N2 - To evaluate the role of passive smoking in the development of lung cancer among nonsmokers, data were pooled from three large incident case-control interview studies. Ninety-nine lung cancer cases and 736 controls never used any form of tobacco. Overall the adjusted odds ratio for lung cancer among nonsmokers ever living with a smoker was 0.8 (95% confidence interval, 0.5-1.3) rising to 1.2 among those exposed for 40 or more years. Persons living with a spouse who smoked cigarettes were at increased risk (adjusted odds ratio, 1.5; 95% confidence interval, 0.8-2.8). When adjusted for age and gender, there was a significant trend in risk with increasing amounts smoked per week by the spouse (P = 0.05) and with cumulative pack-years of exposure (P = 0.03). This effect was limited to females, especially older women whose husbands were heavy smokers. The elevated risk associated with spouse smoking was restricted to squamous and small cell carcinomas (odds ratio, 2.9; 95% confidence interval, 0.9-93), which provides additional evidence linking passive smoking to lung cancer.

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Stemhagen A, Pickle LW, Fontham E. The Relation of Passive Smoking to Lung Cancer. Cancer Research. 1986 Jan 1;46(9):4808-4811.