The role of anticoagulants, antiplatelet agents, and their reversal strategies in the management of intracerebral hemorrhage

Robert F. James, Viktoras Palys, Jason R. Lomboy, J. Richard Lamm, Scott D. Simon

Research output: Contribution to journalArticle

23 Scopus citations


New anticoagulant and antiplatelet medications have been approved and are prescribedwith increased frequency. Intracranial hemorrhage is associated with the use of these medications. Therefore, neurosurgeons need to be aware of these new medications, how they are different from their predecessors, and the strategies for the urgent reversal of their effects. Utilization of intraluminal stents by endovascular neurosurgeons has resulted inthe need to have a thorough understanding of antiplatelet agents. Increased use of dabigatran, rivaroxaban, and apixaban as oral anticoagulants for the treatment of atrial fibrillation and acute deep venous thrombosis has increased despite the lack of known antidotesto these medications.

Original languageEnglish (US)
Article numberE6
JournalNeurosurgical focus
Issue number5
Publication statusPublished - May 1 2013


All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this