The ross operation in children and young adults: A fifteen-year, single-institution experience

Joseph Clark, Linda Pauliks, Ashley Rogerson, Allen Kunselman, John Myers

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: The optimal operation for aortic valve disease in children and young adults remains controversial. The Ross operation offers avoidance of anticoagulation and the potential for growth but is technically demanding and creates double-valve disease. The goal of this study is to report our experience with the Ross operation and the need for reintervention at intermediate follow-up. Methods: A retrospective review of Ross operations in a single surgeon experience from 1992 to 2007 was conducted. All echocardiograms were reevaluated by a single cardiologist. Results: The cohort included 54 patients with a mean age of 13.5 years (range 0.5 to 35 years). Pulmonary autograft implantation was accomplished using root replacement (n = 43), root inclusion (n = 9), and Dacron tube root replacement (n = 2). Follow-up was available for 47 patients (87%) at a mean length of 6.4 years. There were no deaths. Kaplan-Meier estimates of freedom from explantation at 10 years were 100% for the autograft and 71% for the homograft. Autograft insufficiency at latest follow-up was trivial in 37 patients (82%), mild in 6 patients (13%), and moderate in 2 patients (4%). Reintervention for the homograft included balloon dilation in 3 children and conduit change in 5 children (all ≤ 2 years old at initial operation). Conclusions: The Ross operation can be performed in children and adults with low mortality and can provide a durable result for the aortic valve with a low incidence of aortic insufficiency. The need for homograft replacement during follow-up in our series was primarily limited to children who were age 2 years or younger at initial operation.

Original languageEnglish (US)
Pages (from-to)1936-1942
Number of pages7
JournalAnnals of Thoracic Surgery
Volume91
Issue number6
DOIs
StatePublished - Jan 1 2011

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Young Adult
Autografts
Allografts
Aortic Valve
Aortic Diseases
Polyethylene Terephthalates
Kaplan-Meier Estimate
Dilatation
Lung
Mortality
Incidence
Growth

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

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title = "The ross operation in children and young adults: A fifteen-year, single-institution experience",
abstract = "Background: The optimal operation for aortic valve disease in children and young adults remains controversial. The Ross operation offers avoidance of anticoagulation and the potential for growth but is technically demanding and creates double-valve disease. The goal of this study is to report our experience with the Ross operation and the need for reintervention at intermediate follow-up. Methods: A retrospective review of Ross operations in a single surgeon experience from 1992 to 2007 was conducted. All echocardiograms were reevaluated by a single cardiologist. Results: The cohort included 54 patients with a mean age of 13.5 years (range 0.5 to 35 years). Pulmonary autograft implantation was accomplished using root replacement (n = 43), root inclusion (n = 9), and Dacron tube root replacement (n = 2). Follow-up was available for 47 patients (87{\%}) at a mean length of 6.4 years. There were no deaths. Kaplan-Meier estimates of freedom from explantation at 10 years were 100{\%} for the autograft and 71{\%} for the homograft. Autograft insufficiency at latest follow-up was trivial in 37 patients (82{\%}), mild in 6 patients (13{\%}), and moderate in 2 patients (4{\%}). Reintervention for the homograft included balloon dilation in 3 children and conduit change in 5 children (all ≤ 2 years old at initial operation). Conclusions: The Ross operation can be performed in children and adults with low mortality and can provide a durable result for the aortic valve with a low incidence of aortic insufficiency. The need for homograft replacement during follow-up in our series was primarily limited to children who were age 2 years or younger at initial operation.",
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The ross operation in children and young adults : A fifteen-year, single-institution experience. / Clark, Joseph; Pauliks, Linda; Rogerson, Ashley; Kunselman, Allen; Myers, John.

In: Annals of Thoracic Surgery, Vol. 91, No. 6, 01.01.2011, p. 1936-1942.

Research output: Contribution to journalArticle

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T2 - A fifteen-year, single-institution experience

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N2 - Background: The optimal operation for aortic valve disease in children and young adults remains controversial. The Ross operation offers avoidance of anticoagulation and the potential for growth but is technically demanding and creates double-valve disease. The goal of this study is to report our experience with the Ross operation and the need for reintervention at intermediate follow-up. Methods: A retrospective review of Ross operations in a single surgeon experience from 1992 to 2007 was conducted. All echocardiograms were reevaluated by a single cardiologist. Results: The cohort included 54 patients with a mean age of 13.5 years (range 0.5 to 35 years). Pulmonary autograft implantation was accomplished using root replacement (n = 43), root inclusion (n = 9), and Dacron tube root replacement (n = 2). Follow-up was available for 47 patients (87%) at a mean length of 6.4 years. There were no deaths. Kaplan-Meier estimates of freedom from explantation at 10 years were 100% for the autograft and 71% for the homograft. Autograft insufficiency at latest follow-up was trivial in 37 patients (82%), mild in 6 patients (13%), and moderate in 2 patients (4%). Reintervention for the homograft included balloon dilation in 3 children and conduit change in 5 children (all ≤ 2 years old at initial operation). Conclusions: The Ross operation can be performed in children and adults with low mortality and can provide a durable result for the aortic valve with a low incidence of aortic insufficiency. The need for homograft replacement during follow-up in our series was primarily limited to children who were age 2 years or younger at initial operation.

AB - Background: The optimal operation for aortic valve disease in children and young adults remains controversial. The Ross operation offers avoidance of anticoagulation and the potential for growth but is technically demanding and creates double-valve disease. The goal of this study is to report our experience with the Ross operation and the need for reintervention at intermediate follow-up. Methods: A retrospective review of Ross operations in a single surgeon experience from 1992 to 2007 was conducted. All echocardiograms were reevaluated by a single cardiologist. Results: The cohort included 54 patients with a mean age of 13.5 years (range 0.5 to 35 years). Pulmonary autograft implantation was accomplished using root replacement (n = 43), root inclusion (n = 9), and Dacron tube root replacement (n = 2). Follow-up was available for 47 patients (87%) at a mean length of 6.4 years. There were no deaths. Kaplan-Meier estimates of freedom from explantation at 10 years were 100% for the autograft and 71% for the homograft. Autograft insufficiency at latest follow-up was trivial in 37 patients (82%), mild in 6 patients (13%), and moderate in 2 patients (4%). Reintervention for the homograft included balloon dilation in 3 children and conduit change in 5 children (all ≤ 2 years old at initial operation). Conclusions: The Ross operation can be performed in children and adults with low mortality and can provide a durable result for the aortic valve with a low incidence of aortic insufficiency. The need for homograft replacement during follow-up in our series was primarily limited to children who were age 2 years or younger at initial operation.

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