The selection of comparators for randomized controlled trials of health-related behavioral interventions

recommendations of an NIH expert panel

National Institutes of Health Office of Behavioral, Social Sciences Research Expert Panel on Comparator Selection in Behavioral, Social Science Clinical Trials

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Objectives: To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. Study Design and Setting: The National Institutes of Health Office of Behavioral and Social Science Research convened an expert panel to critically review the literature on control or comparison groups for behavioral trials and to develop strategies for improving comparator choices and for resolving controversies and disagreements about comparators. Results: The panel developed a Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. The model indicates that the optimal comparator is the one that best serves the primary purpose of the trial but that the optimal comparator's limitations and barriers to its use must also be taken into account. Conclusion: We developed best practice recommendations for the selection of comparators for health-related behavioral trials. Use of the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials can improve the comparator selection process and help resolve disagreements about comparator choices.

Original languageEnglish (US)
Pages (from-to)74-81
Number of pages8
JournalJournal of Clinical Epidemiology
Volume110
DOIs
StatePublished - Jun 1 2019

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Randomized Controlled Trials
Health
Behavioral Sciences
Social Sciences
National Institutes of Health (U.S.)
Practice Guidelines
Research

All Science Journal Classification (ASJC) codes

  • Epidemiology

Cite this

National Institutes of Health Office of Behavioral, Social Sciences Research Expert Panel on Comparator Selection in Behavioral, & Social Science Clinical Trials (2019). The selection of comparators for randomized controlled trials of health-related behavioral interventions: recommendations of an NIH expert panel. Journal of Clinical Epidemiology, 110, 74-81. https://doi.org/10.1016/j.jclinepi.2019.02.011
National Institutes of Health Office of Behavioral ; Social Sciences Research Expert Panel on Comparator Selection in Behavioral ; Social Science Clinical Trials. / The selection of comparators for randomized controlled trials of health-related behavioral interventions : recommendations of an NIH expert panel. In: Journal of Clinical Epidemiology. 2019 ; Vol. 110. pp. 74-81.
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abstract = "Objectives: To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. Study Design and Setting: The National Institutes of Health Office of Behavioral and Social Science Research convened an expert panel to critically review the literature on control or comparison groups for behavioral trials and to develop strategies for improving comparator choices and for resolving controversies and disagreements about comparators. Results: The panel developed a Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. The model indicates that the optimal comparator is the one that best serves the primary purpose of the trial but that the optimal comparator's limitations and barriers to its use must also be taken into account. Conclusion: We developed best practice recommendations for the selection of comparators for health-related behavioral trials. Use of the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials can improve the comparator selection process and help resolve disagreements about comparator choices.",
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National Institutes of Health Office of Behavioral, Social Sciences Research Expert Panel on Comparator Selection in Behavioral & Social Science Clinical Trials 2019, 'The selection of comparators for randomized controlled trials of health-related behavioral interventions: recommendations of an NIH expert panel', Journal of Clinical Epidemiology, vol. 110, pp. 74-81. https://doi.org/10.1016/j.jclinepi.2019.02.011

The selection of comparators for randomized controlled trials of health-related behavioral interventions : recommendations of an NIH expert panel. / National Institutes of Health Office of Behavioral; Social Sciences Research Expert Panel on Comparator Selection in Behavioral; Social Science Clinical Trials.

In: Journal of Clinical Epidemiology, Vol. 110, 01.06.2019, p. 74-81.

Research output: Contribution to journalReview article

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T1 - The selection of comparators for randomized controlled trials of health-related behavioral interventions

T2 - recommendations of an NIH expert panel

AU - National Institutes of Health Office of Behavioral

AU - Social Sciences Research Expert Panel on Comparator Selection in Behavioral

AU - Social Science Clinical Trials

AU - Freedland, Kenneth E.

AU - King, Abby C.

AU - Ambrosius, Walter T.

AU - Mayo-Wilson, Evan

AU - Mohr, David C.

AU - Czajkowski, Susan M.

AU - Thabane, Lehana

AU - Collins, Linda M.

AU - Rebok, George W.

AU - Treweek, Shaun P.

AU - Cook, Thomas D.

AU - Edinger, Jack D.

AU - Stoney, Catherine M.

AU - Campo, Rebecca A.

AU - Young-Hyman, Deborah

AU - Collins, Linda Marie

PY - 2019/6/1

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N2 - Objectives: To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. Study Design and Setting: The National Institutes of Health Office of Behavioral and Social Science Research convened an expert panel to critically review the literature on control or comparison groups for behavioral trials and to develop strategies for improving comparator choices and for resolving controversies and disagreements about comparators. Results: The panel developed a Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. The model indicates that the optimal comparator is the one that best serves the primary purpose of the trial but that the optimal comparator's limitations and barriers to its use must also be taken into account. Conclusion: We developed best practice recommendations for the selection of comparators for health-related behavioral trials. Use of the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials can improve the comparator selection process and help resolve disagreements about comparator choices.

AB - Objectives: To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. Study Design and Setting: The National Institutes of Health Office of Behavioral and Social Science Research convened an expert panel to critically review the literature on control or comparison groups for behavioral trials and to develop strategies for improving comparator choices and for resolving controversies and disagreements about comparators. Results: The panel developed a Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. The model indicates that the optimal comparator is the one that best serves the primary purpose of the trial but that the optimal comparator's limitations and barriers to its use must also be taken into account. Conclusion: We developed best practice recommendations for the selection of comparators for health-related behavioral trials. Use of the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials can improve the comparator selection process and help resolve disagreements about comparator choices.

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National Institutes of Health Office of Behavioral, Social Sciences Research Expert Panel on Comparator Selection in Behavioral, Social Science Clinical Trials. The selection of comparators for randomized controlled trials of health-related behavioral interventions: recommendations of an NIH expert panel. Journal of Clinical Epidemiology. 2019 Jun 1;110:74-81. https://doi.org/10.1016/j.jclinepi.2019.02.011