The state of antibody catalysis

David B. Smithrud, Stephen Benkovic

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

One of the fascinations of catalytic antibodies is the possibility of harnessing the mechanisms available to enzymes for chemical transformation and applying them to the broad realm of chemistry encountered in organic synthesis. Recently, the catalytic repertoire of antibodies has been extended to include mechanistically more complex bimolecular reactions and the immunological response to the hapten can be more thoroughly examined as a result of the advent of new screening technology using bacterial phages or auxotrophic cell lines.

Original languageEnglish (US)
Pages (from-to)459-466
Number of pages8
JournalCurrent Opinion in Biotechnology
Volume8
Issue number4
DOIs
StatePublished - Jan 1 1997

Fingerprint

Catalytic Antibodies
Bacteriophages
Catalysis
Antibodies
Screening
Enzymes
Cells
Synthetic Chemistry Techniques
Haptens
Technology
Cell Line

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

Smithrud, David B. ; Benkovic, Stephen. / The state of antibody catalysis. In: Current Opinion in Biotechnology. 1997 ; Vol. 8, No. 4. pp. 459-466.
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The state of antibody catalysis. / Smithrud, David B.; Benkovic, Stephen.

In: Current Opinion in Biotechnology, Vol. 8, No. 4, 01.01.1997, p. 459-466.

Research output: Contribution to journalArticle

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