The transformylase enzymes in de novo purine biosynthesis

Stephen J. Benkovic

Research output: Contribution to journalReview article

24 Scopus citations

Abstract

The two transformylase enzymes in de novo purine biosynthesis require 10-formyl-H4folate as a cofactor, but can utilize efficiently differing synthetic analogs allowing their selective assay or inhibition. They, with a multifunctional enzyme responsible for cofactor synthesis, constitute a unique and possibly interacting subset within the de novo pathway.

Original languageEnglish (US)
Pages (from-to)320-322
Number of pages3
JournalTrends in Biochemical Sciences
Volume9
Issue number7
DOIs
StatePublished - Jul 1984

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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