The unpredictable character of congenital cystic lung lesions

Kevin K. Roggin, Christopher K. Breuer, Stephen R. Carr, Katrine Hansen, Arlet G. Kurkchubasche, Conrad W. Wesselhoeft, Thomas F. Tracy, Francois I. Luks

Research output: Contribution to journalArticle

90 Scopus citations

Abstract

Background: The spectrum of congenital cystic disease of the lung ranges from hydrops and neonatal respiratory distress to asymptomatic lesions. Surgical management is dictated by the presence of symptoms, recurrent infection, and the potential risk of malignant transformation. Methods: Since 1995, all consecutive patients with congenital cystic lung lesions underwent follow-up for symptoms, treatment, and correlation of presumptive with pathological diagnosis. Results: Twelve cystic tung lesions were identified. Seven were diagnosed with mediastinal shift in utero; in 6 of 7, the shift subsequently resolved. Overall, 6 of 7 lesions that were followed up serially decreased in size. Two patients were symptomatic in utero; 1 underwent thoracoamniotic shunting, 1 pleurocentesis for impending hydrops. Postnatally, these 2, and 2 other newborns required urgent surgery. Five of 8 asymptomatic patients had elective resection by 16 months, and 4 await operation. In 6 of the 9 surgical cases (67%), there was a discrepancy between preoperative and pathological diagnosis. There were 4 hybrid congenital cystic adenomatoid malformation (CCAM)/sequestrations. Conclusions: At least 6 of 7 congenital cystic lung lesions decreased in size regardless of gestational age or presence of mediastinal shift. Antenatal intervention is therefore rarely indicated. Hybrid morphology may necessitate resection of stable, asymptomatic lesions to prevent the theoretical concern for associated malignancies as well as other complications of CCAM. Copyright (C) 2000 by W.B. Saunders Company.

Original languageEnglish (US)
Pages (from-to)801-805
Number of pages5
JournalJournal of pediatric surgery
Volume35
Issue number5
DOIs
Publication statusPublished - May 2000

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

Roggin, K. K., Breuer, C. K., Carr, S. R., Hansen, K., Kurkchubasche, A. G., Wesselhoeft, C. W., ... Luks, F. I. (2000). The unpredictable character of congenital cystic lung lesions. Journal of pediatric surgery, 35(5), 801-805. https://doi.org/10.1053/jpsu.2000.6088