The use of bacteriophages of the family Cystoviridae as surrogates for H5N1 highly pathogenic avian influenza viruses in persistence and inactivation studies

Noreen J. Adcock, Eugene W. Rice, Mano Sivaganesan, Justin David Brown, David E. Stallknecht, David E. Swayne

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Two bacteriophages, φ6 and φ8, were investigated as potential surrogates for H5N1 highly pathogenic avian influenza virus in persistence and chlorine inactivation studies in water. In the persistence studies, φ6 and φ8 remained infectious at least as long as the H5N1 viruses at both 17 and 28°C in fresh water, but results varied in salinated water. The bacteriophage φ6 also exhibited a slightly higher chlorine resistance than that of the H5N1 viruses. Based upon these findings, the bacteriophages may have potential for use as surrogates in persistence and inactivation studies in fresh water.

Original languageEnglish (US)
Pages (from-to)1362-1366
Number of pages5
JournalJournal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering
Volume44
Issue number13
DOIs
StatePublished - Dec 1 2009

Fingerprint

Cystoviridae
Bacteriophages
Influenza in Birds
Orthomyxoviridae
Viruses
H5N1 Subtype Influenza A Virus
Chlorine
Fresh Water
Water

All Science Journal Classification (ASJC) codes

  • Environmental Engineering
  • Medicine(all)

Cite this

@article{7ada891fd9514a9ca2915040c51888b5,
title = "The use of bacteriophages of the family Cystoviridae as surrogates for H5N1 highly pathogenic avian influenza viruses in persistence and inactivation studies",
abstract = "Two bacteriophages, φ6 and φ8, were investigated as potential surrogates for H5N1 highly pathogenic avian influenza virus in persistence and chlorine inactivation studies in water. In the persistence studies, φ6 and φ8 remained infectious at least as long as the H5N1 viruses at both 17 and 28°C in fresh water, but results varied in salinated water. The bacteriophage φ6 also exhibited a slightly higher chlorine resistance than that of the H5N1 viruses. Based upon these findings, the bacteriophages may have potential for use as surrogates in persistence and inactivation studies in fresh water.",
author = "Adcock, {Noreen J.} and Rice, {Eugene W.} and Mano Sivaganesan and Brown, {Justin David} and Stallknecht, {David E.} and Swayne, {David E.}",
year = "2009",
month = "12",
day = "1",
doi = "10.1080/10934520903217054",
language = "English (US)",
volume = "44",
pages = "1362--1366",
journal = "Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering",
issn = "1093-4529",
publisher = "Taylor and Francis Ltd.",
number = "13",

}

The use of bacteriophages of the family Cystoviridae as surrogates for H5N1 highly pathogenic avian influenza viruses in persistence and inactivation studies. / Adcock, Noreen J.; Rice, Eugene W.; Sivaganesan, Mano; Brown, Justin David; Stallknecht, David E.; Swayne, David E.

In: Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering, Vol. 44, No. 13, 01.12.2009, p. 1362-1366.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The use of bacteriophages of the family Cystoviridae as surrogates for H5N1 highly pathogenic avian influenza viruses in persistence and inactivation studies

AU - Adcock, Noreen J.

AU - Rice, Eugene W.

AU - Sivaganesan, Mano

AU - Brown, Justin David

AU - Stallknecht, David E.

AU - Swayne, David E.

PY - 2009/12/1

Y1 - 2009/12/1

N2 - Two bacteriophages, φ6 and φ8, were investigated as potential surrogates for H5N1 highly pathogenic avian influenza virus in persistence and chlorine inactivation studies in water. In the persistence studies, φ6 and φ8 remained infectious at least as long as the H5N1 viruses at both 17 and 28°C in fresh water, but results varied in salinated water. The bacteriophage φ6 also exhibited a slightly higher chlorine resistance than that of the H5N1 viruses. Based upon these findings, the bacteriophages may have potential for use as surrogates in persistence and inactivation studies in fresh water.

AB - Two bacteriophages, φ6 and φ8, were investigated as potential surrogates for H5N1 highly pathogenic avian influenza virus in persistence and chlorine inactivation studies in water. In the persistence studies, φ6 and φ8 remained infectious at least as long as the H5N1 viruses at both 17 and 28°C in fresh water, but results varied in salinated water. The bacteriophage φ6 also exhibited a slightly higher chlorine resistance than that of the H5N1 viruses. Based upon these findings, the bacteriophages may have potential for use as surrogates in persistence and inactivation studies in fresh water.

UR - http://www.scopus.com/inward/record.url?scp=77952557449&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952557449&partnerID=8YFLogxK

U2 - 10.1080/10934520903217054

DO - 10.1080/10934520903217054

M3 - Article

C2 - 20183493

AN - SCOPUS:77952557449

VL - 44

SP - 1362

EP - 1366

JO - Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering

JF - Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering

SN - 1093-4529

IS - 13

ER -