Theoretical and experimental comparison of tissue phantoms using white light spectroscopy

Kaloyan A. Popov, Timothy Kurzweg

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

White light spectroscopy has the potential to be used as an optical biopsy method, as backscattered light data can be related to the cellular nucleus size. In this paper, we compare experimental backscattering results against the general Mie theory simulations. Our experimental technique obtains results in terms of intensity vs. wavelength. We also use optical filters, to limit the source spectrum, and when converting the backscattered data into the Fourier domain, we obtain characteristic frequencies which describe the scatterer size. Phantom tissues, comprised of polystyrene spheres in a liquid or gel, are used for the experiments.

Original languageEnglish (US)
Title of host publicationBiomedical Applications of Light Scattering V
DOIs
StatePublished - Mar 31 2011
EventBiomedical Applications of Light Scattering V - San Francisco, CA, United States
Duration: Jan 22 2011Jan 24 2011

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7907
ISSN (Print)1605-7422

Conference

ConferenceBiomedical Applications of Light Scattering V
CountryUnited States
CitySan Francisco, CA
Period1/22/111/24/11

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Popov, K. A., & Kurzweg, T. (2011). Theoretical and experimental comparison of tissue phantoms using white light spectroscopy. In Biomedical Applications of Light Scattering V [790702] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7907). https://doi.org/10.1117/12.875231