Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease

S. Yokota, T. Kuriyama, Y. Takahashi, M. Mori, Hiroko Shike, M. Ibe, T. Mitsuda, Y. Aihara

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

To assess Raynaud's phenomenon objectively, thermographic estimation of hands and fingers was performed before and after the disease- and Raynaud's phenomenon-directed therapy in 3 children with mixed connective tissue disease. All the cases were positive in Raynaud's phenomenon, and the surface temperature of their hands and fingers were decreased even before cold challenge. After the cold provocation test at 4 degrees C for 10 sec., the temperature of all or some of the fingers were rapidly decreased, and the recovery of surface temperature of these fingers were markedly delayed. Even after methylprednisolone pulse therapy the pattern of the finger temperature were essentially unchanged, suggesting that steroids are not effective in the treatment of Raynaud's phenomenon. The long-term administration of vitamin-E, oral prostaglandin E1, and/or serotonin-receptor inhibitor were also proved to be not beneficial in improving Raynaud's phenomenon. Thus, thermography is useful in diagnosing Raynaud's phenomenon objectively, in determining the efficacy of anti-Raynaud drugs, and in estimating long-term course of the phenomenon.

Original languageEnglish (US)
Pages (from-to)955-960
Number of pages6
JournalRyūmachi. [Rheumatism]
Volume34
Issue number6
StatePublished - Jan 1 1994

Fingerprint

Mixed Connective Tissue Disease
Raynaud Disease
Fingers
Temperature
Hand
Alprostadil
Serotonin Receptors
Methylprednisolone
Vitamin E
Therapeutics
Steroids
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Rheumatology

Cite this

Yokota, S., Kuriyama, T., Takahashi, Y., Mori, M., Shike, H., Ibe, M., ... Aihara, Y. (1994). Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease. Ryūmachi. [Rheumatism], 34(6), 955-960.
Yokota, S. ; Kuriyama, T. ; Takahashi, Y. ; Mori, M. ; Shike, Hiroko ; Ibe, M. ; Mitsuda, T. ; Aihara, Y. / Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease. In: Ryūmachi. [Rheumatism]. 1994 ; Vol. 34, No. 6. pp. 955-960.
@article{4a80b012dfb641a69f2178487c42ae43,
title = "Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease",
abstract = "To assess Raynaud's phenomenon objectively, thermographic estimation of hands and fingers was performed before and after the disease- and Raynaud's phenomenon-directed therapy in 3 children with mixed connective tissue disease. All the cases were positive in Raynaud's phenomenon, and the surface temperature of their hands and fingers were decreased even before cold challenge. After the cold provocation test at 4 degrees C for 10 sec., the temperature of all or some of the fingers were rapidly decreased, and the recovery of surface temperature of these fingers were markedly delayed. Even after methylprednisolone pulse therapy the pattern of the finger temperature were essentially unchanged, suggesting that steroids are not effective in the treatment of Raynaud's phenomenon. The long-term administration of vitamin-E, oral prostaglandin E1, and/or serotonin-receptor inhibitor were also proved to be not beneficial in improving Raynaud's phenomenon. Thus, thermography is useful in diagnosing Raynaud's phenomenon objectively, in determining the efficacy of anti-Raynaud drugs, and in estimating long-term course of the phenomenon.",
author = "S. Yokota and T. Kuriyama and Y. Takahashi and M. Mori and Hiroko Shike and M. Ibe and T. Mitsuda and Y. Aihara",
year = "1994",
month = "1",
day = "1",
language = "English (US)",
volume = "34",
pages = "955--960",
journal = "Ryumachi",
issn = "0300-9157",
publisher = "Nihon Ryumachi Gakkai",
number = "6",

}

Yokota, S, Kuriyama, T, Takahashi, Y, Mori, M, Shike, H, Ibe, M, Mitsuda, T & Aihara, Y 1994, 'Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease', Ryūmachi. [Rheumatism], vol. 34, no. 6, pp. 955-960.

Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease. / Yokota, S.; Kuriyama, T.; Takahashi, Y.; Mori, M.; Shike, Hiroko; Ibe, M.; Mitsuda, T.; Aihara, Y.

In: Ryūmachi. [Rheumatism], Vol. 34, No. 6, 01.01.1994, p. 955-960.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease

AU - Yokota, S.

AU - Kuriyama, T.

AU - Takahashi, Y.

AU - Mori, M.

AU - Shike, Hiroko

AU - Ibe, M.

AU - Mitsuda, T.

AU - Aihara, Y.

PY - 1994/1/1

Y1 - 1994/1/1

N2 - To assess Raynaud's phenomenon objectively, thermographic estimation of hands and fingers was performed before and after the disease- and Raynaud's phenomenon-directed therapy in 3 children with mixed connective tissue disease. All the cases were positive in Raynaud's phenomenon, and the surface temperature of their hands and fingers were decreased even before cold challenge. After the cold provocation test at 4 degrees C for 10 sec., the temperature of all or some of the fingers were rapidly decreased, and the recovery of surface temperature of these fingers were markedly delayed. Even after methylprednisolone pulse therapy the pattern of the finger temperature were essentially unchanged, suggesting that steroids are not effective in the treatment of Raynaud's phenomenon. The long-term administration of vitamin-E, oral prostaglandin E1, and/or serotonin-receptor inhibitor were also proved to be not beneficial in improving Raynaud's phenomenon. Thus, thermography is useful in diagnosing Raynaud's phenomenon objectively, in determining the efficacy of anti-Raynaud drugs, and in estimating long-term course of the phenomenon.

AB - To assess Raynaud's phenomenon objectively, thermographic estimation of hands and fingers was performed before and after the disease- and Raynaud's phenomenon-directed therapy in 3 children with mixed connective tissue disease. All the cases were positive in Raynaud's phenomenon, and the surface temperature of their hands and fingers were decreased even before cold challenge. After the cold provocation test at 4 degrees C for 10 sec., the temperature of all or some of the fingers were rapidly decreased, and the recovery of surface temperature of these fingers were markedly delayed. Even after methylprednisolone pulse therapy the pattern of the finger temperature were essentially unchanged, suggesting that steroids are not effective in the treatment of Raynaud's phenomenon. The long-term administration of vitamin-E, oral prostaglandin E1, and/or serotonin-receptor inhibitor were also proved to be not beneficial in improving Raynaud's phenomenon. Thus, thermography is useful in diagnosing Raynaud's phenomenon objectively, in determining the efficacy of anti-Raynaud drugs, and in estimating long-term course of the phenomenon.

UR - http://www.scopus.com/inward/record.url?scp=0028719289&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028719289&partnerID=8YFLogxK

M3 - Article

C2 - 7863385

AN - SCOPUS:0028719289

VL - 34

SP - 955

EP - 960

JO - Ryumachi

JF - Ryumachi

SN - 0300-9157

IS - 6

ER -

Yokota S, Kuriyama T, Takahashi Y, Mori M, Shike H, Ibe M et al. Thermographic assessment of Raynaud's phenomenon in childhood mixed connective tissue disease. Ryūmachi. [Rheumatism]. 1994 Jan 1;34(6):955-960.