Abstract
Measurement of the serum thyroglobulin level may be more sensitive than total-body scan using sodium iodide 131 for detecting recurrences from well-differentiated thyroid cancer. We have evaluated the merit of these two methods through a retrospective chart review of patients followed up at the Milton S. Hershey Medical Center, Hershey, Pa. We found that in 17 (45%) of 38 follow-up visits, the presence of interfering antibodies prevented the measurement of serum thyroglobulin levels. Furthermore, such determination was less sensitive than iodine 131 total-body scan in detecting residual thyroid tissue and/or cancer in the neck area. We concluded that iodine 131 total-body scan is the preferable method of follow-up, particularly when the goal of therapy is complete ablation of thyroid tissue.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 437-439 |
| Number of pages | 3 |
| Journal | Archives of Internal Medicine |
| Volume | 150 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 5 1990 |
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All Science Journal Classification (ASJC) codes
- Internal Medicine
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Thyroglobulin measurement vs iodine 131 total-body scan for follow-up of well differentiated thyroid cancer. / Aiello, D. P.; Manni, Andrea.
In: Archives of Internal Medicine, Vol. 150, No. 2, 05.03.1990, p. 437-439.Research output: Contribution to journal › Article
TY - JOUR
T1 - Thyroglobulin measurement vs iodine 131 total-body scan for follow-up of well differentiated thyroid cancer
AU - Aiello, D. P.
AU - Manni, Andrea
PY - 1990/3/5
Y1 - 1990/3/5
N2 - Measurement of the serum thyroglobulin level may be more sensitive than total-body scan using sodium iodide 131 for detecting recurrences from well-differentiated thyroid cancer. We have evaluated the merit of these two methods through a retrospective chart review of patients followed up at the Milton S. Hershey Medical Center, Hershey, Pa. We found that in 17 (45%) of 38 follow-up visits, the presence of interfering antibodies prevented the measurement of serum thyroglobulin levels. Furthermore, such determination was less sensitive than iodine 131 total-body scan in detecting residual thyroid tissue and/or cancer in the neck area. We concluded that iodine 131 total-body scan is the preferable method of follow-up, particularly when the goal of therapy is complete ablation of thyroid tissue.
AB - Measurement of the serum thyroglobulin level may be more sensitive than total-body scan using sodium iodide 131 for detecting recurrences from well-differentiated thyroid cancer. We have evaluated the merit of these two methods through a retrospective chart review of patients followed up at the Milton S. Hershey Medical Center, Hershey, Pa. We found that in 17 (45%) of 38 follow-up visits, the presence of interfering antibodies prevented the measurement of serum thyroglobulin levels. Furthermore, such determination was less sensitive than iodine 131 total-body scan in detecting residual thyroid tissue and/or cancer in the neck area. We concluded that iodine 131 total-body scan is the preferable method of follow-up, particularly when the goal of therapy is complete ablation of thyroid tissue.
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UR - http://www.scopus.com/inward/citedby.url?scp=0025060934&partnerID=8YFLogxK
U2 - 10.1001/archinte.150.2.437
DO - 10.1001/archinte.150.2.437
M3 - Article
C2 - 2105703
AN - SCOPUS:0025060934
VL - 150
SP - 437
EP - 439
JO - JAMA Internal Medicine
JF - JAMA Internal Medicine
SN - 2168-6106
IS - 2
ER -