Time-dependent change in fresh autologous pericardium applied for posterior mitral annuloplasty: Degree of calcification and its influence on the repaired mitral valve

Takashi Miura, Kiyoyuki Eishi, Ichiro Sakamoto, Shiro Yamachika, Kouji Hashizume, Kentaro Yamane, Kazuyoshi Tanigawa, Seiji Matsukuma, Shun Nakaji

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3 Scopus citations

Abstract

Objective: To investigate the degree of calcification of fresh autologous pericardium applied for posterior mitral annuloplasty and its influence on the repaired mitral valve. Methods: Thirty-nine patients (31 degenerative and 8 infective endocarditis; mean age at surgery: 62 ± 11 years) were enrolled in this study. Sixteen-slice multi-detector computed tomography was performed to identify calcification of autologous pericardium. The mean clinical follow-up was 4.6 ± 2.6 years (maximum 8.8 years) and the mean computed tomography follow-up period was 3.6 ± 2.5 years (maximum 7.6 years) after surgery. Results: Pericardial calcification was detected in 15 patients. The earliest detection of calcification was 2.5 years after surgery. There was a weak correlation between pericardial calcification and postoperative years (Pearson's product correlation coefficient: 0.476; p = 0.0019). However, severe calcification of autologous pericardium did not occur in any case. There was no association between pericardial calcification and recurrent mitral regurgitation (p = 0.1145). The mean mitral valve orifice area and the mean transmitral pressure gradient in the 15 patients with calcification were 3.0 ± 0.6 cm 2 and 2.1 ± 1.0 mmHg, respectively. Conclusions: Calcification of the fresh autologous pericardium increased with postoperative years. It had no adverse effects on repaired mitral valve in the short-term follow-up period. We will report the findings once again when the follow-up reaches 10 years.

Original languageEnglish (US)
Pages (from-to)334-340
Number of pages7
JournalGeneral Thoracic and Cardiovascular Surgery
Volume60
Issue number6
DOIs
StatePublished - Jun 1 2012

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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