Time-dependent change in fresh autologous pericardium applied for posterior mitral annuloplasty: Degree of calcification and its influence on the repaired mitral valve

Takashi Miura, Kiyoyuki Eishi, Ichiro Sakamoto, Shiro Yamachika, Kouji Hashizume, Kentaro Yamane, Kazuyoshi Tanigawa, Seiji Matsukuma, Shun Nakaji

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: To investigate the degree of calcification of fresh autologous pericardium applied for posterior mitral annuloplasty and its influence on the repaired mitral valve. Methods: Thirty-nine patients (31 degenerative and 8 infective endocarditis; mean age at surgery: 62 ± 11 years) were enrolled in this study. Sixteen-slice multi-detector computed tomography was performed to identify calcification of autologous pericardium. The mean clinical follow-up was 4.6 ± 2.6 years (maximum 8.8 years) and the mean computed tomography follow-up period was 3.6 ± 2.5 years (maximum 7.6 years) after surgery. Results: Pericardial calcification was detected in 15 patients. The earliest detection of calcification was 2.5 years after surgery. There was a weak correlation between pericardial calcification and postoperative years (Pearson's product correlation coefficient: 0.476; p = 0.0019). However, severe calcification of autologous pericardium did not occur in any case. There was no association between pericardial calcification and recurrent mitral regurgitation (p = 0.1145). The mean mitral valve orifice area and the mean transmitral pressure gradient in the 15 patients with calcification were 3.0 ± 0.6 cm 2 and 2.1 ± 1.0 mmHg, respectively. Conclusions: Calcification of the fresh autologous pericardium increased with postoperative years. It had no adverse effects on repaired mitral valve in the short-term follow-up period. We will report the findings once again when the follow-up reaches 10 years.

Original languageEnglish (US)
Pages (from-to)334-340
Number of pages7
JournalGeneral Thoracic and Cardiovascular Surgery
Volume60
Issue number6
DOIs
StatePublished - Jun 1 2012

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Mitral Valve Annuloplasty
Pericardium
Mitral Valve
Tomography
Mitral Valve Insufficiency
Endocarditis
Pressure

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Miura, Takashi ; Eishi, Kiyoyuki ; Sakamoto, Ichiro ; Yamachika, Shiro ; Hashizume, Kouji ; Yamane, Kentaro ; Tanigawa, Kazuyoshi ; Matsukuma, Seiji ; Nakaji, Shun. / Time-dependent change in fresh autologous pericardium applied for posterior mitral annuloplasty : Degree of calcification and its influence on the repaired mitral valve. In: General Thoracic and Cardiovascular Surgery. 2012 ; Vol. 60, No. 6. pp. 334-340.
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Time-dependent change in fresh autologous pericardium applied for posterior mitral annuloplasty : Degree of calcification and its influence on the repaired mitral valve. / Miura, Takashi; Eishi, Kiyoyuki; Sakamoto, Ichiro; Yamachika, Shiro; Hashizume, Kouji; Yamane, Kentaro; Tanigawa, Kazuyoshi; Matsukuma, Seiji; Nakaji, Shun.

In: General Thoracic and Cardiovascular Surgery, Vol. 60, No. 6, 01.06.2012, p. 334-340.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Time-dependent change in fresh autologous pericardium applied for posterior mitral annuloplasty

T2 - Degree of calcification and its influence on the repaired mitral valve

AU - Miura, Takashi

AU - Eishi, Kiyoyuki

AU - Sakamoto, Ichiro

AU - Yamachika, Shiro

AU - Hashizume, Kouji

AU - Yamane, Kentaro

AU - Tanigawa, Kazuyoshi

AU - Matsukuma, Seiji

AU - Nakaji, Shun

PY - 2012/6/1

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N2 - Objective: To investigate the degree of calcification of fresh autologous pericardium applied for posterior mitral annuloplasty and its influence on the repaired mitral valve. Methods: Thirty-nine patients (31 degenerative and 8 infective endocarditis; mean age at surgery: 62 ± 11 years) were enrolled in this study. Sixteen-slice multi-detector computed tomography was performed to identify calcification of autologous pericardium. The mean clinical follow-up was 4.6 ± 2.6 years (maximum 8.8 years) and the mean computed tomography follow-up period was 3.6 ± 2.5 years (maximum 7.6 years) after surgery. Results: Pericardial calcification was detected in 15 patients. The earliest detection of calcification was 2.5 years after surgery. There was a weak correlation between pericardial calcification and postoperative years (Pearson's product correlation coefficient: 0.476; p = 0.0019). However, severe calcification of autologous pericardium did not occur in any case. There was no association between pericardial calcification and recurrent mitral regurgitation (p = 0.1145). The mean mitral valve orifice area and the mean transmitral pressure gradient in the 15 patients with calcification were 3.0 ± 0.6 cm 2 and 2.1 ± 1.0 mmHg, respectively. Conclusions: Calcification of the fresh autologous pericardium increased with postoperative years. It had no adverse effects on repaired mitral valve in the short-term follow-up period. We will report the findings once again when the follow-up reaches 10 years.

AB - Objective: To investigate the degree of calcification of fresh autologous pericardium applied for posterior mitral annuloplasty and its influence on the repaired mitral valve. Methods: Thirty-nine patients (31 degenerative and 8 infective endocarditis; mean age at surgery: 62 ± 11 years) were enrolled in this study. Sixteen-slice multi-detector computed tomography was performed to identify calcification of autologous pericardium. The mean clinical follow-up was 4.6 ± 2.6 years (maximum 8.8 years) and the mean computed tomography follow-up period was 3.6 ± 2.5 years (maximum 7.6 years) after surgery. Results: Pericardial calcification was detected in 15 patients. The earliest detection of calcification was 2.5 years after surgery. There was a weak correlation between pericardial calcification and postoperative years (Pearson's product correlation coefficient: 0.476; p = 0.0019). However, severe calcification of autologous pericardium did not occur in any case. There was no association between pericardial calcification and recurrent mitral regurgitation (p = 0.1145). The mean mitral valve orifice area and the mean transmitral pressure gradient in the 15 patients with calcification were 3.0 ± 0.6 cm 2 and 2.1 ± 1.0 mmHg, respectively. Conclusions: Calcification of the fresh autologous pericardium increased with postoperative years. It had no adverse effects on repaired mitral valve in the short-term follow-up period. We will report the findings once again when the follow-up reaches 10 years.

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