Tissue-Engineered Peripheral Nerve Guide Fabrication Techniques

Dianna Y. Nguyen, Richard T. Tran, Francesco Costanzo, Jian Yang

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

The clinical need for readily available and viable conduits to circumvent the use of nerve autografts has driven research to the development of biodegradable tissue-engineered nerve guides (TENGs) to bridge and restore the function of transected peripheral nerves. In the search for an ideal TENG, researchers have introduced increasingly more sophisticated fabrication techniques in combination with a variety of biomaterials to produce organized porous structures conducive to nerve regeneration and functional recovery. The intent of this chapter is to delineate the TENG fabrication techniques that have been studied to enhance the regenerative effectiveness of critically sized peripheral nerve defects. In addition, important design criteria, biomaterial options, and new perspectives on future technologies toward the development of clinically viable solutions are discussed.

Original languageEnglish (US)
Title of host publicationPain, Treatment, Injury, Disease and Future Directions
PublisherElsevier
Pages971-992
Number of pages22
Volume2
ISBN (Electronic)9780128026953
ISBN (Print)9780128026533
DOIs
StatePublished - Apr 23 2015

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Nerve Tissue
Peripheral Nerves
Biocompatible Materials
Nerve Regeneration
Autografts
Research Personnel
Technology
Research

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Nguyen, D. Y., Tran, R. T., Costanzo, F., & Yang, J. (2015). Tissue-Engineered Peripheral Nerve Guide Fabrication Techniques. In Pain, Treatment, Injury, Disease and Future Directions (Vol. 2, pp. 971-992). Elsevier. https://doi.org/10.1016/B978-0-12-802653-3.00109-3
Nguyen, Dianna Y. ; Tran, Richard T. ; Costanzo, Francesco ; Yang, Jian. / Tissue-Engineered Peripheral Nerve Guide Fabrication Techniques. Pain, Treatment, Injury, Disease and Future Directions. Vol. 2 Elsevier, 2015. pp. 971-992
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Nguyen, DY, Tran, RT, Costanzo, F & Yang, J 2015, Tissue-Engineered Peripheral Nerve Guide Fabrication Techniques. in Pain, Treatment, Injury, Disease and Future Directions. vol. 2, Elsevier, pp. 971-992. https://doi.org/10.1016/B978-0-12-802653-3.00109-3

Tissue-Engineered Peripheral Nerve Guide Fabrication Techniques. / Nguyen, Dianna Y.; Tran, Richard T.; Costanzo, Francesco; Yang, Jian.

Pain, Treatment, Injury, Disease and Future Directions. Vol. 2 Elsevier, 2015. p. 971-992.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Nguyen DY, Tran RT, Costanzo F, Yang J. Tissue-Engineered Peripheral Nerve Guide Fabrication Techniques. In Pain, Treatment, Injury, Disease and Future Directions. Vol. 2. Elsevier. 2015. p. 971-992 https://doi.org/10.1016/B978-0-12-802653-3.00109-3