Tissue engineering: A promising therapeutic approach to necrotizing enterocolitis

Christa N. Grant, Tracy C. Grikscheit

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Tissue engineering is a promising potential candidate for treating intestinal failure resulting from necrotizing enterocolitis. This requires the acquisition, preparation and implantation of autologous organoid units. This may be affected by the complexities of periods of storage of viable donor tissue and delayed implantation. This chapter addresses the development, methodology, and application of tissue-engineered intestine in the experimental and clinical setting. Tissue engineering has the potential of avoiding the inherent toxicities of intestinal transplantation and prolonged immunosuppression.

Original languageEnglish (US)
Pages (from-to)112-116
Number of pages5
JournalSeminars in pediatric surgery
Volume22
Issue number2
DOIs
StatePublished - May 1 2013

Fingerprint

Necrotizing Enterocolitis
Tissue Engineering
Organoids
Immunosuppression
Intestines
Transplantation
Tissue Donors
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

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Tissue engineering : A promising therapeutic approach to necrotizing enterocolitis. / Grant, Christa N.; Grikscheit, Tracy C.

In: Seminars in pediatric surgery, Vol. 22, No. 2, 01.05.2013, p. 112-116.

Research output: Contribution to journalArticle

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