TY - JOUR
T1 - Tobacco exposure and maternal psychopathology
T2 - Impact on toddler problem behavior
AU - Godleski, Stephanie A.
AU - Eiden, Rina D.
AU - Schuetze, Pamela
AU - Colder, Craig R.
AU - Huestis, Marilyn A.
N1 - Funding Information:
We thank the staff of the Growing Up Healthy project and the participating families for their support. The first author was supported by a National Institute of Alcohol Abuse and Alcoholism training grant to the Research Institute on Addictions ( T32AA007583 ). Research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health ( R01DA019632 ). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Publisher Copyright:
© 2016
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Prenatal exposure to tobacco has consistently predicted later problem behavior for children. However, little is known about developmental mechanisms underlying this association. We examined a conceptual model for the association between prenatal tobacco exposure and child problem behavior in toddlerhood via indirect paths through fetal growth, maternal depression, and maternal aggressive disposition in early infancy and via maternal warmth and sensitivity and infant negative affect in later infancy. The sample consisted of 258 mother–child dyads recruited during pregnancy and assessed periodically at 2, 9, and 16 months of child age. Pathways via maternal depression and infant negative affect to toddler problem behavior were significant. Further, combined tobacco and marijuana exposure during pregnancy and reduced fetal growth also demonstrated important associations with infant negative affect and subsequent problem behavior. These results highlight the importance of considering the role of maternal negative affect and poor fetal growth as risk factors in the context of prenatal exposure.
AB - Prenatal exposure to tobacco has consistently predicted later problem behavior for children. However, little is known about developmental mechanisms underlying this association. We examined a conceptual model for the association between prenatal tobacco exposure and child problem behavior in toddlerhood via indirect paths through fetal growth, maternal depression, and maternal aggressive disposition in early infancy and via maternal warmth and sensitivity and infant negative affect in later infancy. The sample consisted of 258 mother–child dyads recruited during pregnancy and assessed periodically at 2, 9, and 16 months of child age. Pathways via maternal depression and infant negative affect to toddler problem behavior were significant. Further, combined tobacco and marijuana exposure during pregnancy and reduced fetal growth also demonstrated important associations with infant negative affect and subsequent problem behavior. These results highlight the importance of considering the role of maternal negative affect and poor fetal growth as risk factors in the context of prenatal exposure.
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U2 - 10.1016/j.ntt.2016.07.003
DO - 10.1016/j.ntt.2016.07.003
M3 - Article
C2 - 27498223
AN - SCOPUS:84990064087
VL - 57
SP - 87
EP - 94
JO - Neurobehavioral toxicology
JF - Neurobehavioral toxicology
SN - 0892-0362
ER -