Tobacco use following liver transplantation for alcoholic liver disease: An underestimated problem

Andrea DiMartini, Lubna Javed, Sarah Russell, Mary Amanda Dew, Mary Grace Fitzgerald, Ashok Jain, John Fung

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Alcohol and tobacco use commonly co-occur, with at least 90% of those with an alcohol problem also using tobacco. Thus, 3 years ago when we discovered higher rate of late deaths due to lung and oropharyngeal cancer in patients who had received a transplant for alcoholic liver disease (ALD), we hypothesized that these patients were continuing to expose themselves to tobacco after liver transplantation (post-LTX) and that this behavior was increasing their risk for cancer. We subsequently began a prospective investigation of post-LTX tobacco use in patients having undergone LTX for ALD (n = 172). For 33 recipients we had data starting from our first assessment at 3 months post-LTX and for this subgroup we report on the details of the timing of tobacco use resumption and the redevelopment of nicotine addiction. We found that on average more than 40% are smoking across all time periods. ALD recipients resume smoking early post-LTX, increase their consumption over time, and quickly become tobacco dependent. These data highlight an underrecognized serious health risk for these patients and demonstrate our need for more stringent clinical monitoring and intervention for tobacco use in the pre- and post-LTX periods.

Original languageEnglish (US)
Pages (from-to)679-683
Number of pages5
JournalLiver Transplantation
Volume11
Issue number6
DOIs
StatePublished - Jun 1 2005

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Alcoholic Liver Diseases
Tobacco Use
Liver Transplantation
Tobacco
Smoking
Alcohols
Oropharyngeal Neoplasms
Nicotine
Lung Neoplasms
Transplants
Mortality
Health
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery
  • Hepatology
  • Transplantation

Cite this

DiMartini, A., Javed, L., Russell, S., Dew, M. A., Fitzgerald, M. G., Jain, A., & Fung, J. (2005). Tobacco use following liver transplantation for alcoholic liver disease: An underestimated problem. Liver Transplantation, 11(6), 679-683. https://doi.org/10.1002/lt.20385
DiMartini, Andrea ; Javed, Lubna ; Russell, Sarah ; Dew, Mary Amanda ; Fitzgerald, Mary Grace ; Jain, Ashok ; Fung, John. / Tobacco use following liver transplantation for alcoholic liver disease : An underestimated problem. In: Liver Transplantation. 2005 ; Vol. 11, No. 6. pp. 679-683.
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DiMartini, A, Javed, L, Russell, S, Dew, MA, Fitzgerald, MG, Jain, A & Fung, J 2005, 'Tobacco use following liver transplantation for alcoholic liver disease: An underestimated problem', Liver Transplantation, vol. 11, no. 6, pp. 679-683. https://doi.org/10.1002/lt.20385

Tobacco use following liver transplantation for alcoholic liver disease : An underestimated problem. / DiMartini, Andrea; Javed, Lubna; Russell, Sarah; Dew, Mary Amanda; Fitzgerald, Mary Grace; Jain, Ashok; Fung, John.

In: Liver Transplantation, Vol. 11, No. 6, 01.06.2005, p. 679-683.

Research output: Contribution to journalArticle

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